Rabbit Anti-GATAD2B Polyclonal Antibody – Cat# MBS6301361

GATAD2B Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the GATAD2B antibody detected the GATAD2B protein (arrow).

GATAD2B Antibody – Rabbit Polyclonal

Name: GATAD2B Antibody; Polyclonal; Rabbit; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6301361
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6301361

GATAD2B has transcriptional repressor activity. Targets MBD3 to discrete loci in the nucleus. More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GATAD2B, Polyclonal Antibody

Full Product Name

GATAD2B, NT (GATAD2B, KIAA1150, Transcriptional repressor p66-beta, GATA zinc finger domain-containing protein 2B, p66/p68) (Azide free) (HRP)

Product Gene Name

anti-GATAD2B antibody

Product Synonym Names

GATAD2B; KIAA1150; Transcriptional repressor p66-beta; GATA zinc finger domain-containing protein 2B; p66/p68

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Mouse

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

65,261 Da

OMIM

gene 615074

3D Structure

ModBase 3D Structure for Q8WXI9

Immunogen

GATAD2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GATAD2B.

Conjugate

HRP

Note

Preservative Free

Product Categories/Family for anti-GATAD2B antibody

Antibodies; Transcription Factors; Zinc (Ring) Finger

Applications Tested/Suitable for anti-GATAD2B antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-GATAD2B antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-GATAD2B antibody

Ichikawa, S., et al. J. Bone Miner. Res. 23(10):1680-1688(2008). Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007). Olsen, J.V., et al. Cell 127(3):635-648(2006). Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006). Brackertz, M., et al. Nucleic Acids Res. 34(2):397-406(2006).

Other Notes

Small volumes of anti-GATAD2B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GATAD2B purchase

MBS6301361 is an antibody targeting GATAD2B. Also known as GATAD2B, NT (GATAD2B, KIAA1150, Transcriptional repressor p66-beta, GATA zinc finger domain-containing protein 2B, p66/p68) (Azide free) (HRP). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GATAD2B. It may not necessarily be applicable to this product.

NCBI GI #

21218438

NCBI GeneID

57459

NCBI Accession #

NP_065750.1

UniProt Primary Accession #

Q8WXI9

UniProt Secondary Accession #

Q5VUR2; Q7LG68; Q9ULS0; D3DUZ2

UniProt Related Accession #

Q8WXI9

GenBank Nucleotide #

NM_020699.2

NCBI Official Full Name

transcriptional repressor p66-beta

NCBI Official Synonym Full Names

GATA zinc finger domain containing 2B

NCBI Official Symbol

GATAD2B

NCBI Official Synonym Symbols

p68; MRD18; P66beta

UniProt Protein Name

Transcriptional repressor p66-beta

UniProt Synonym Protein Names

GATA zinc finger domain-containing protein 2B; p66/p68

Protein Family

Transcriptional repressor

UniProt Gene Name

GATAD2B

UniProt Synonym Gene Names

KIAA1150

UniProt Entry Name

P66B_HUMAN

NCBI Protein Information

transcriptional repressor p66-beta; p66/p68; GATA zinc finger domain-containing protein 2B; transcription repressor p66 beta component of the MeCP1 complex

UniProt Comments for GATAD2B

GATAD2B: a transcriptional repressor belonging to the MeCP1 histone deacetylase complex. The MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomes.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: nucleoplasm; protein complex; nuclear chromatin; nuclear speck

Molecular Function: nucleosomal DNA binding; zinc ion binding; transcription factor activity

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; ATP-dependent chromatin remodeling

Disease: Mental Retardation, Autosomal Dominant 18

Research Articles on GATAD2B

1. Detailed clinical description showed that all four individuals with a GATAD2B aberration had a distinctive phenotype with childhood hypotonia, severe intellectual disability.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GATAD2B antibody

Reference Product	PubMed Publications
MBD3 antibody	>2 publications with GATAD2B and MBD3
GATAD2A antibody	>1 publications with GATAD2B and GATAD2A
CHD3 antibody	>1 publications with GATAD2B and CHD3
CHD4 antibody	>1 publications with GATAD2B and CHD4
MTA2 antibody	>1 publications with GATAD2B and MTA2
RBBP7 antibody	>1 publications with GATAD2B and RBBP7
RBBP4 antibody	>1 publications with GATAD2B and RBBP4
HDAC1 antibody	>1 publications with GATAD2B and HDAC1
MBD2 antibody	>1 publications with GATAD2B and MBD2

Pathways associated with anti-GATAD2B antibody

Products by Pathway	Pathway Diagram
Chromatin Modifying Enzymes Pathway antibodies	Chromatin Modifying Enzymes Pathway Diagram
Chromatin Organization Pathway antibodies	Chromatin Organization Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
HDACs Deacetylate Histones Pathway antibodies	HDACs Deacetylate Histones Pathway Diagram
RNA Polymerase I Promoter Clearance Pathway antibodies	RNA Polymerase I Promoter Clearance Pathway Diagram
RNA Polymerase I Transcription Pathway antibodies	RNA Polymerase I Transcription Pathway Diagram
RNA Polymerase I Transcription Initiation Pathway antibodies	RNA Polymerase I Transcription Initiation Pathway Diagram
RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway antibodies	RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway Diagram
Signaling Events Mediated By HDAC Class I Pathway antibodies	Signaling Events Mediated By HDAC Class I Pathway Diagram

Diseases associated with anti-GATAD2B antibody

Disease Name	Pubmed Publications
Mental Disorders Antibodies	>2 publications with GATAD2B and Mental Disorders
Neurobehavioral Manifestations Antibodies	>2 publications with GATAD2B and Neurobehavioral Manifestations
Nervous System Diseases Antibodies	>2 publications with GATAD2B and Nervous System Diseases
Learning Disorders Antibodies	>2 publications with GATAD2B and Learning Disorders
Abnormalities, Multiple Antibodies	>1 publications with GATAD2B and Abnormalities, Multiple
Cognition Disorders Antibodies	>1 publications with GATAD2B and Cognition Disorders

Organs/Tissues associated with anti-GATAD2B antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>1 publications with GATAD2B and Kidney
Testis Antibodies	>1 publications with GATAD2B and Testis
Lung Antibodies	>1 publications with GATAD2B and Lung
Mouth Antibodies	>1 publications with GATAD2B and Mouth