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GTF2H2C Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6304889

Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II (By similarity). More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GTF2H2C, Polyclonal Antibody
Full Product Name
GTF2H2C, CT (GTF2H2C, General transcription factor IIH subunit 2-like protein, General transcription factor IIH polypeptide 2-like protein) (APC)
Product Gene Name
anti-GTF2H2C antibody
Product Synonym Names
GTF2H2C; General transcription factor IIH subunit 2-like protein; General transcription factor IIH polypeptide 2-like protein
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
44,452 Da
3D Structure
ModBase 3D Structure for Q6P1K8
Immunogen
GTF2H2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 321-351 amino acids from the C-terminal region of human GTF2H2C.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-GTF2H2C antibody

Antibodies; Transcription Factors
Applications Tested/Suitable for anti-GTF2H2C antibody
Immunofluorescence (IF), FLISA, Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-GTF2H2C antibody
IF: 1:10-50
FLISA: 1:1,000
IHC: 1:10-50
WB: 1:100-500
Applications are based on unconjugated antibody.

Immunohistochemistry (IHC) of anti-GTF2H2C antibody

GTF2H2C Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GTF2H2C Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-GTF2H2C Polyclonal Antibody – Cat# MBS6304889

Western Blot (WB) of anti-GTF2H2C antibody

GTF2H2C Antibody (C-term) western blot analysis in Hela,293,NCI-H460,NCI-H292,A2058 cell line lysates (35ug/lane).This demonstrates the GTF2H2C antibody detected the GTF2H2C protein (arrow).
Rabbit Anti-GTF2H2C Polyclonal Antibody, Western Blot (WB) – Cat# MBS6304889

Immunofluorescence (IF) of anti-GTF2H2C antibody

Confocal immunofluorescent analysis of GTF2H2C Antibody (C-term) with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).
Rabbit Anti-GTF2H2C Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS6304889

Product References and Citations for anti-GTF2H2C antibody

Schmutz, J., et al. Nature 431(7006):268-274(2004).

Other Notes

Small volumes of anti-GTF2H2C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GTF2H2C purchase

MBS6304889 is an antibody targeting GTF2H2C. Also known as GTF2H2C, CT (GTF2H2C, General transcription factor IIH subunit 2-like protein, General transcription factor IIH polypeptide 2-like protein) (APC). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GTF2H2C. It may not necessarily be applicable to this product.

NCBI GI #
148922852
NCBI GeneID
728340
NCBI Accession #
NP_001092198.1
NCBI Related Accession #
NP_001035955.1
UniProt Primary Accession #
Q6P1K8
UniProt Secondary Accession #
A6NED9; A8K8J6; B2RCU4; B7ZW39
UniProt Related Accession #
Q6P1K8
GenBank Nucleotide #
NM_001098728.1
NCBI Official Full Name
general transcription factor IIH subunit 2-like protein
NCBI Official Synonym Full Names
GTF2H2 family member C
NCBI Official Symbol
GTF2H2C
NCBI Official Synonym Symbols
GTF2H2C_2
UniProt Protein Name
General transcription factor IIH subunit 2-like protein
UniProt Synonym Protein Names
General transcription factor IIH polypeptide 2-like protein
Protein Family
General transcription factor IIH subunit 2-like protein
UniProt Gene Name
GTF2H2C
UniProt Synonym Gene Names
GTF2H2D
NCBI Protein Information
general transcription factor IIH subunit 2-like protein

UniProt Comments for GTF2H2C

Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-GTF2H2C antibody

 Products by Pathway  Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 DNA Repair Pathway antibodies  DNA Repair Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Dual Incision In GG-NER Pathway antibodies  Dual Incision In GG-NER Pathway Diagram
 Dual Incision In TC-NER Pathway antibodies  Dual Incision In TC-NER Pathway Diagram
 Epigenetic Regulation Of Gene Expression Pathway antibodies  Epigenetic Regulation Of Gene Expression Pathway Diagram
 Formation Of HIV Elongation Complex In The Absence Of HIV Tat Pathway antibodies  Formation Of HIV Elongation Complex In The Absence Of HIV Tat Pathway Diagram
 Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway antibodies  Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway Diagram
 Formation Of Incision Complex In GG-NER Pathway antibodies  Formation Of Incision Complex In GG-NER Pathway Diagram

Organs/Tissues associated with anti-GTF2H2C antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >1 publications with GTF2H2C and Lung
 Embryonic Tissue Antibodies  >1 publications with GTF2H2C and Embryonic Tissue
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