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TOB2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS630517

TOB2 belongs to the TOB /BTG1 family of antiproliferative proteins, which are involved in the regulation of cell cycle progression. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TOB2, Polyclonal Antibody
Full Product Name
TOB2, NT (Protein Tob2, Transducer of erbB-2 2, Protein Tob4, KIAA1663, TOB4, TROB2)
Product Gene Name
Product Synonym Names
Anti -TOB2, NT (Protein Tob2, Transducer of erbB-2 2, Protein Tob4, KIAA1663, TOB4, TROB2)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human TOB2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
36,632 Da
Chromosome Location
Chromosome: 22; NC_000022.10 (41829492..41843027, complement). Location: 22q13.2
OMIM
607396
3D Structure
ModBase 3D Structure for Q14106
Immunogen
Synthetic peptide selected from the N-terminal region of human TOB2 (KLH).
Applications Tested/Suitable for anti-TOB2 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-TOB2 antibody
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:50

Western Blot (WB) of anti-TOB2 antibody

Western Blot analysis in HepG2 cell line lysates (35ug/lane) using MBS630517. TOB2 (arrow) was detected using MBS630517.
Rabbit Anti-TOB2 Polyclonal Antibody – Cat# MBS630517

Immunohistochemistry (IHC) of anti-TOB2 antibody

Immunohistochemistry analysis in formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with TMBS630517, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of tMBS630517 for immunohistochemistry.
Rabbit Anti-TOB2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS630517

Other Notes

Small volumes of anti-TOB2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TOB2 purchase

MBS630517 is an antibody targeting TOB2. Also known as TOB2, NT (Protein Tob2, Transducer of erbB-2 2, Protein Tob4, KIAA1663, TOB4, TROB2). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TOB2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
TOB2
NCBI Official Synonym Full Names
transducer of ERBB2, 2
NCBI Official Symbol
TOB2
NCBI Official Synonym Symbols
TOB4; TOBL; TROB2
UniProt Protein Name
Protein Tob2
UniProt Synonym Protein Names
Protein Tob4; Transducer of erbB-2 2
Protein Family
UniProt Gene Name
TOB2
UniProt Synonym Gene Names
KIAA1663; TOB4; TROB2
UniProt Entry Name
TOB2_HUMAN
NCBI Protein Information
protein Tob2; protein Tob4; OTTHUMP00000198833; OTTHUMP00000198834; transducer of erbB-2 2

NCBI Summary for TOB2

TOB2 belongs to the TOB (see TOB1; MIM 605523)/BTG1 (MIM 109580) family of antiproliferative proteins, which are involved in the regulation of cell cycle progression.[supplied by OMIM]

UniProt Comments for TOB2

TOB2: Anti-proliferative protein inhibits cell cycle progression from the G0/G1 to S phases. Belongs to the BTG family.

Chromosomal Location of Human Ortholog: 22q13.2

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; vitamin D receptor binding

Biological Process: negative regulation of osteoclast differentiation; negative regulation of cell proliferation; regulation of gene expression; female gamete generation; positive regulation of ossification
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TOB2 antibody

 Reference Product  PubMed Publications
 CNOT7 antibody  >3 publications with TOB2 and CNOT7

Pathways associated with anti-TOB2 antibody

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