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Glycophorin-B (GYPB) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6305190

MBS6305190 is an antibody targeting GYPB. Also known as Glycophorin-B, ID (GYPB, GPB,, PAS-3, SS-active sialoglycoprotein, Sialoglycoprotein delta, CD235b) (MaxLight 405). Reactive in Human. Host: Rabbit. More details

$1025 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Glycophorin-B (GYPB), Polyclonal Antibody
Full Product Name
Glycophorin-B, ID (GYPB, GPB,, PAS-3, SS-active sialoglycoprotein, Sialoglycoprotein delta, CD235b) (MaxLight 405)
Product Gene Name
Product Synonym Names
GYPB; GPB; Glycophorin-B; PAS-3; SS-active sialoglycoprotein; Sialoglycoprotein delta; CD235b
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.
Purity/Purification
Purified by Protein A and Peptide Affinity Chromatography.
Specificity
Recognizes human Glycophorin-B.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
6,352 Da
OMIM
J02982 mRNA
3D Structure
ModBase 3D Structure for P06028
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids aa22-51 in the central region of human Glycophorin-B, UniProt Accession #P06028; NP_002091.3
Conjugate
MaxLight405
Note
Preservative Free

Product Categories/Family for anti-GYPB antibody

Applications Tested/Suitable for anti-GYPB antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-GYPB antibody
IHC: 1:10-1:50
WB: 1:1000
Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-GYPB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GYPB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
glycophorin-B isoform 1
NCBI Official Synonym Full Names
glycophorin B (MNS blood group)
NCBI Official Symbol
GYPB
NCBI Official Synonym Symbols
SS; GPB; MNS; PAS-3; CD235b
UniProt Protein Name
Glycophorin-B
UniProt Synonym Protein Names
PAS-3; SS-active sialoglycoprotein; Sialoglycoprotein delta; CD_antigen: CD235b
Protein Family
UniProt Gene Name
GYPB
UniProt Synonym Gene Names
GPB
NCBI Protein Information
glycophorin-B; SS-active sialoglycoprotein; Ss blood group; sialoglycoprotein delta

NCBI Summary for GYPB

Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
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UniProt Comments for GYPB

GYPB: This protein is a minor sialoglycoprotein in erythrocyte membranes. Belongs to the glycophorin-A family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q31.21

Cellular Component: integral component of plasma membrane; plasma membrane

Molecular Function: protein binding

Biological Process: leukocyte migration

Disease: Malaria, Susceptibility To
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-GYPB antibody

Organs/Tissues associated with anti-GYPB antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >29 publications with GYPB and Blood
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