• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

PCTAIRE1 (CDK16) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS630691

The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells. This gene is thought to escape X inactivation. Two transcript… More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PCTAIRE1 (CDK16), Polyclonal Antibody
Full Product Name
PCTAIRE1, NT (PCTAIRE Protein Kinase 1, PCTAIRE-motif Protein Kinase 1, PCTAIRE 1, PCTAIRE, PCTGAIRE, PCTK1, Cell Division Protein Kinase 16, Cyclin-dependent Kinase 16, CDK16, FLJ16665, Serine/threonine Protein Kinase PCTAIRE-1)
Product Gene Name
anti-CDK16 antibody
Product Synonym Names
Anti -PCTAIRE1, NT (PCTAIRE Protein Kinase 1, PCTAIRE-motif Protein Kinase 1, PCTAIRE 1, PCTAIRE, PCTGAIRE, PCTK1, Cell Division Protein Kinase 16, Cyclin-dependent Kinase 16, CDK16, FLJ16665, Serine/threonine Protein Kinase PCTAIRE-1)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human PCTK1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
55,716 Da
Chromosome Location
Chromosome: X; NC_000023.10 (47077445..47089396). Location: Xp11
OMIM
311550
3D Structure
ModBase 3D Structure for Q00536
Immunogen
Synthetic peptide selected from the C-terminal region of human PCTK1 (KLH).

Product Categories/Family for anti-CDK16 antibody

Antibodies; Abs to Protein Kinases
Applications Tested/Suitable for anti-CDK16 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-CDK16 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500

Western Blot (WB) of anti-CDK16 antibody

Western blot analysis of PCTK1 Antibody (C-term) in HepG2 tissue lysate. PCTK1 (arrow) was detected using the purified Pab;
Rabbit Anti-CDK16 Polyclonal Antibody – Cat# MBS630691

Western Blot (WB) of anti-CDK16 antibody

Western blot analysis of PCTK1 (arrow) using rabbit polyclonal PCTK1 C-term . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PCTK1 gene (Lane 2).
Rabbit Anti-CDK16 Polyclonal Antibody, Western Blot (WB) – Cat# MBS630691

Other Notes

Small volumes of anti-CDK16 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDK16 purchase

MBS630691 is an antibody targeting CDK16. Also known as PCTAIRE1, NT (PCTAIRE Protein Kinase 1, PCTAIRE-motif Protein Kinase 1, PCTAIRE 1, PCTAIRE, PCTGAIRE, PCTK1, Cell Division Protein Kinase 16, Cyclin-dependent Kinase 16, CDK16, FLJ16665, Serine/threonine Protein Kinase PCTAIRE-1). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CDK16. It may not necessarily be applicable to this product.

NCBI GI #
530421473
NCBI GeneID
5127
NCBI Accession #
XP_005272672.1
UniProt Primary Accession #
Q00536
UniProt Secondary Accession #
A8K280; B7Z7C8; J3KN74; J3KQP7
UniProt Related Accession #
Q00536
GenBank Nucleotide #
XM_005272615.1
NCBI Official Full Name
cyclin-dependent kinase 16 isoform X3
NCBI Official Synonym Full Names
cyclin-dependent kinase 16
NCBI Official Symbol
CDK16
NCBI Official Synonym Symbols
PCTK1; PCTAIRE; PCTAIRE1; PCTGAIRE
UniProt Protein Name
Cyclin-dependent kinase 16
UniProt Synonym Protein Names
Cell division protein kinase 16; PCTAIRE-motif protein kinase 1; Serine/threonine-protein kinase PCTAIRE-1
Protein Family
Cyclin-dependent kinase
UniProt Gene Name
CDK16
UniProt Synonym Gene Names
PCTAIRE1; PCTK1
UniProt Entry Name
CDK16_HUMAN
NCBI Protein Information
cyclin-dependent kinase 16; PCTAIRE-motif protein kinase 1; cell division protein kinase 16; serine/threonine-protein kinase PCTAIRE-1

NCBI Summary for CDK16

The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2009]
Show more

UniProt Comments for CDK16

CDK16: May play a role in signal transduction cascades in terminally differentiated cells. Found in a complex containing CABLES1, CDK17 and TDRD7. Interacts with YWHAH, YWHAQ and YWHAZ. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

Protein type: Cell cycle regulation; Protein kinase, Ser/Thr (non-receptor); Motility/polarity/chemotaxis; EC 2.7.11.22; Kinase, protein; Protein kinase, CMGC; CMGC group; CDK family; TAIRE subfamily; CDK/TAIRE subfamily

Chromosomal Location of Human Ortholog: Xp11

Cellular Component: microtubule cytoskeleton; synaptic vesicle; extrinsic to internal side of plasma membrane; transport vesicle; neuron projection; cytoplasm; plasma membrane; cell junction

Molecular Function: protein serine/threonine kinase activity; protein binding; cyclin-dependent protein kinase activity; ATP binding

Biological Process: growth hormone secretion; exocytosis; regulation of cell cycle; spermatogenesis; protein amino acid phosphorylation; neurite development
Show more

Research Articles on CDK16

1. a novel function of BRSK2 in the regulation of GSIS in beta-cells via a PCTAIRE1-dependent mechanism and suggest that BRSK2 is an attractive target for developing novel diabetic drugs.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-CDK16 antibody

 Disease Name  Pubmed Publications
 Infertility, Female Antibodies  >1 publications with CDK16 and Infertility, Female
 Infertility, Male Antibodies  >1 publications with CDK16 and Infertility, Male

Organs/Tissues associated with anti-CDK16 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with CDK16 and Brain
 Testis Antibodies  >2 publications with CDK16 and Testis
 Epididymis Antibodies  >1 publications with CDK16 and Epididymis
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000