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MOSC2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS630693

Catalytic component of the benzamidoxime prodrug-converting complex, a complex required to reduce N-hydroxylated structures, such as benzamidoxime prodrug. Benzamidoxime is an amidine prodrug produced by N-hydroxylation which is used to enhance… More details

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Product Overview

Online Datasheet in PDF
Product Name
MOSC2, Polyclonal Antibody
Full Product Name
MOSC2, CT (MOSC Domain-containing Protein 2 Mitochondrial, FLJ20605, RP11-270A6.1)
Product Gene Name
anti-MOSC2 antibody
Product Synonym Names
Anti -MOSC2, CT (MOSC Domain-containing Protein 2 Mitochondrial, FLJ20605, RP11-270A6.1)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human MOSC2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
38,023 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (220921676..220957599). Location: 1q41
3D Structure
ModBase 3D Structure for Q969Z3
Immunogen
Synthetic peptide selected from the C-terminal region of human MOSC2 (KLH).

Product Categories/Family for anti-MOSC2 antibody

Antibodies; Abs to Signal Transduction
Applications Tested/Suitable for anti-MOSC2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-MOSC2 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500

Western Blot (WB) of anti-MOSC2 antibody

Western blot analysis of MOSC2 Antibody (C-term) in Hela cell line lysates (35ug/lane). MOSC2 (arrow) was detected using the purified Pab.
Rabbit Anti-MOSC2 Polyclonal Antibody – Cat# MBS630693

Immunohistochemistry (IHC) of anti-MOSC2 antibody

Formalin-fixed and paraffin-embedded human lung carcinoma reacted with MOSC2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-MOSC2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS630693

Flow Cytometry (FC/FACS) of anti-MOSC2 antibody

MOSC2 Antibody (C-term) flow cytometry analysis of Hela cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-MOSC2 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS630693

Western Blot (WB) of anti-MOSC2 antibody

Western blot analysis of MOSC2 (arrow) using rabbit polyclonal MOSC2 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MOSC2 gene.
Rabbit Anti-MOSC2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS630693

Other Notes

Small volumes of anti-MOSC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MOSC2 purchase

MBS630693 is an antibody targeting MOSC2. Also known as MOSC2, CT (MOSC Domain-containing Protein 2 Mitochondrial, FLJ20605, RP11-270A6.1). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MOSC2. It may not necessarily be applicable to this product.

NCBI GI #
31542713
NCBI GeneID
54996
NCBI Accession #
NP_060368.2
UniProt Primary Accession #
Q969Z3
UniProt Secondary Accession #
Q0JSK7; Q5VT67; Q5VXC7; Q7L317; Q9H066; Q9NWU0; B2D0R5; D3DTB3
UniProt Related Accession #
Q969Z3
GenBank Nucleotide #
NM_017898.3
NCBI Official Full Name
MOSC domain-containing protein 2, mitochondrial
NCBI Official Synonym Full Names
MOCO sulphurase C-terminal domain containing 2
NCBI Official Symbol
MOSC2
NCBI Official Synonym Symbols
FLJ20605; RP11-270A6.1
UniProt Protein Name
MOSC domain-containing protein 2, mitochondrial
UniProt Gene Name
MOSC2
UniProt Entry Name
MOSC2_HUMAN
NCBI Protein Information
MOSC domain-containing protein 2, mitochondrial; OTTHUMP00000035465

UniProt Comments for MOSC2

MOSC2: As a component of the benzamidoxime prodrug-converting complex required to reduce N-hydroxylated prodrugs, such as benzamidoxime. Also able to reduce N(omega)-hydroxy-L-arginine (NOHA) and N(omega)-hydroxy-N(delta)-methyl-L-arginine (NHAM) into L-arginine and N(delta)-methyl-L-arginine, respectively. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.-.-.-; Oxidoreductase; Mitochondrial

Chromosomal Location of Human Ortholog: 1q41

Cellular Component: mitochondrial outer membrane; mitochondrion; mitochondrial inner membrane; peroxisome

Molecular Function: molybdopterin cofactor binding; nitrate reductase activity; molybdenum ion binding; pyridoxal phosphate binding

Biological Process: detoxification of nitrogen compound; nitrate metabolic process
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Research Articles on MOSC2

1. Arc1(MOSC-1) and Arc2(MOSC-2) proteins are monomeric in their active forms.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-MOSC2 antibody

 Organ/Tissue Name  Pubmed Publications
 Connective Tissue Antibodies  >1 publications with MOSC2 and Connective Tissue
 Muscle Antibodies  >1 publications with MOSC2 and Muscle
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