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Histone H2B (HIST1H2BB) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6306951

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core… More details

$1060 / 0.1 mL +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Histone H2B (HIST1H2BB), Polyclonal Antibody
Full Product Name
Histone H2B, NT (HIST1H2BB, H2BFF, HIST1H2BE, Histone H2B type 1-B, Histone H2B.1, Histone H2B.f) (MaxLight 490)
Product Gene Name
Product Synonym Names
HIST1H2BB; H2BFF; HIST1H2BE; Histone H2B type 1-B; Histone H2B.1; Histone H2B.f
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
13,950 Da
OMIM
602803
3D Structure
ModBase 3D Structure for P33778
Immunogen
HIST1H2BB/HIST1H2BE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HIST1H2BB/HIST1H2BE.
Conjugate
MaxLight490
Note
Preservative Free

Product Categories/Family for anti-HIST1H2BB antibody

Applications Tested/Suitable for anti-HIST1H2BB antibody
Western Blot (WB), FLISA
Application Notes for anti-HIST1H2BB antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-HIST1H2BB antibody

Kim, S.C., et al. Mol. Cell 23(4):607-618(2006). Pavri, R., et al. Cell 125(4):703-717(2006). Bonenfant, D., et al. Mol. Cell Proteomics 5(3):541-552(2006). Zhu, B., et al. Mol. Cell 20(4):601-611(2005). Golebiowski, F., et al. Mol. Cell. Biochem. 279 (1-2), 133-139 (2005).

Other Notes

Small volumes of anti-HIST1H2BB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HIST1H2BB purchase

MBS6306951 is an antibody targeting HIST1H2BB. Also known as Histone H2B, NT (HIST1H2BB, H2BFF, HIST1H2BE, Histone H2B type 1-B, Histone H2B.1, Histone H2B.f) (MaxLight 490). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HIST1H2BB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
histone H2B type 1-B
NCBI Official Synonym Full Names
histone cluster 1, H2bb
NCBI Official Symbol
HIST1H2BB
NCBI Official Synonym Symbols
H2B.1; H2B/f; H2BFF
UniProt Protein Name
Histone H2B type 1-B
UniProt Synonym Protein Names
Histone H2B.1; Histone H2B.f; H2B/f
Protein Family
UniProt Gene Name
HIST1H2BB
UniProt Synonym Gene Names
H2BFF; H2B/f
UniProt Entry Name
H2B1B_HUMAN
NCBI Protein Information
histone H2B type 1-B; H2B histone family, member F; histone 1, H2bb; histone H2B.1; histone H2B.f

UniProt Comments for HIST1H2BB

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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