• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

IFT88 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6309411

This gene encodes a member of the tetratrico peptide repeat (TPR) family. Mutations of a similar gene in mouse can cause polycystic kidney disease. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]. More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IFT88, Polyclonal Antibody
Full Product Name
IFT88, CT (IFT88, TG737, TTC10, Intraflagellar transport protein 88 homolog, Recessive polycystic kidney disease protein Tg737 homolog, Tetratricopeptide repeat protein 10) (Biotin)
Product Gene Name
anti-IFT88 antibody
Product Synonym Names
IFT88; TG737; TTC10; Intraflagellar transport protein 88 homolog; Recessive polycystic kidney disease protein Tg737 homolog; Tetratricopeptide repeat protein 10
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
94,270 Da
OMIM
600595
3D Structure
ModBase 3D Structure for Q13099
Immunogen
IFT88 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 798-827 amino acids from the C-terminal region of human IFT88.
Conjugate
Biotin
Note
Preservative Free

Product Categories/Family for anti-IFT88 antibody

Antibodies; Tetratricopeptide Repeat Proteins
Applications Tested/Suitable for anti-IFT88 antibody
Immunofluorescence (IF), ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-IFT88 antibody
IF: 1:10-50
ELISA: 1:1,000
IHC: 1:10-50
WB: 1:100-500
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-IFT88 antibody

IFT88 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the IFT88 antibody detected the IFT88 protein (arrow).
Rabbit Anti-IFT88 Polyclonal Antibody – Cat# MBS6309411

Western Blot (WB) of anti-IFT88 antibody

IFT88 Antibody (C-term) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the IFT88 antibody detected the IFT88 protein (arrow).
Rabbit Anti-IFT88 Polyclonal Antibody, Western Blot (WB) – Cat# MBS6309411

Immunohistochemistry (IHC) of anti-IFT88 antibody

IFT88 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IFT88 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-IFT88 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6309411

Immunofluorescence (IF) of anti-IFT88 antibody

Confocal immunofluorescent analysis of IFT88 Antibody (C-term) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor555 phalloidin (red). DAPI was used to stain the cell nuclear (blue).
Rabbit Anti-IFT88 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS6309411

Product References and Citations for anti-IFT88 antibody

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Robert, A., et al. J. Cell. Sci. 120 (PT 4), 628-637 (2007): Khanna, H., et al. J. Biol. Chem. 280(39):33580-33587(2005). Lehner, B., et al. Genomics 83(1):153-167(2004). Harrington, J.J., et al. Nat. Biotechnol. 19(5):440-445(2001).

Other Notes

Small volumes of anti-IFT88 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IFT88 purchase

MBS6309411 is an antibody targeting IFT88. Also known as IFT88, CT (IFT88, TG737, TTC10, Intraflagellar transport protein 88 homolog, Recessive polycystic kidney disease protein Tg737 homolog, Tetratricopeptide repeat protein 10) (Biotin). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IFT88. It may not necessarily be applicable to this product.

NCBI GI #
28329439
NCBI GeneID
8100
NCBI Accession #
NP_006522.2
UniProt Primary Accession #
Q13099
UniProt Secondary Accession #
Q5SZJ6; Q8N719; A2A491; B4DUS2
UniProt Related Accession #
Q13099
GenBank Nucleotide #
NM_006531.3
NCBI Official Full Name
intraflagellar transport protein 88 homolog isoform 2
NCBI Official Synonym Full Names
intraflagellar transport 88
NCBI Official Symbol
IFT88
NCBI Official Synonym Symbols
DAF19; TG737; TTC10; hTg737; D13S1056E
UniProt Protein Name
Intraflagellar transport protein 88 homolog
UniProt Synonym Protein Names
Recessive polycystic kidney disease protein Tg737 homolog; Tetratricopeptide repeat protein 10; TPR repeat protein 10
Protein Family
Intraflagellar transport protein
UniProt Gene Name
IFT88
UniProt Synonym Gene Names
TG737; TTC10; TPR repeat protein 10
NCBI Protein Information
intraflagellar transport protein 88 homolog; polaris homolog; TPR repeat protein 10; tetratricopeptide repeat domain 10; intraflagellar transport 88 homolog; tetratricopeptide repeat protein 10; recessive polycystic kidney disease protein Tg737 homolog; p

UniProt Comments for IFT88

Involved in primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IFT88 antibody

 Reference Product  PubMed Publications
 IFT52 antibody  >9 publications with IFT88 and IFT52
 IFT172 antibody  >9 publications with IFT88 and IFT172
 GLI3 antibody  >6 publications with IFT88 and GLI3
 GLI2 antibody  >5 publications with IFT88 and GLI2
 IFT81 antibody  >3 publications with IFT88 and IFT81
 IFT74 antibody  >2 publications with IFT88 and IFT74

Pathways associated with anti-IFT88 antibody

 Products by Pathway  Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 Hedgehog Signaling Events Mediated By Gli Proteins Pathway antibodies  Hedgehog Signaling Events Mediated By Gli Proteins Pathway Diagram

Diseases associated with anti-IFT88 antibody

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >23 publications with IFT88 and Kidney Diseases
 Polycystic Kidney, Autosomal Recessive Antibodies  >11 publications with IFT88 and Polycystic Kidney, Autosomal Recessive
 Brain Diseases Antibodies  >5 publications with IFT88 and Brain Diseases
 Liver Diseases Antibodies  >4 publications with IFT88 and Liver Diseases
 Inflammation Antibodies  >4 publications with IFT88 and Inflammation
 Liver Neoplasms Antibodies  >4 publications with IFT88 and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >3 publications with IFT88 and Carcinoma, Hepatocellular
 Hyperplasia Antibodies  >3 publications with IFT88 and Hyperplasia
 Polydactyly Antibodies  >3 publications with IFT88 and Polydactyly
 Hypertrophy Antibodies  >2 publications with IFT88 and Hypertrophy

Organs/Tissues associated with anti-IFT88 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >24 publications with IFT88 and Kidney
 Eye Antibodies  >12 publications with IFT88 and Eye
 Embryonic Tissue Antibodies  >7 publications with IFT88 and Embryonic Tissue
 Liver Antibodies  >5 publications with IFT88 and Liver
 Heart Antibodies  >5 publications with IFT88 and Heart
 Skin Antibodies  >4 publications with IFT88 and Skin
 Muscle Antibodies  >4 publications with IFT88 and Muscle
 Brain Antibodies  >4 publications with IFT88 and Brain
 Blood Antibodies  >3 publications with IFT88 and Blood
 Testis Antibodies  >3 publications with IFT88 and Testis
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000