Fatty Acid Binding Protein, Heart, Adipocyte (FABP7) Antibody – Rabbit Polyclonal

Fatty acids are important for general cellular metabolism. FABPs fatty acid binding proteins) are a group of cytoplasmic, small mol wt (14-15kD) and proteins that has widespread tissue distribution. FABPs are quite abundant (3-5% of total cellular protein). At least 7 FABPs, FABP1-7, have been cloned and characterized from various tissues. FABPs can bind long-chain fatty acid, fatty-acid acyl-CoA and acyl-L-carnitine. Several different isoform of FABP have been identified and generally referred to by tissue type (liver, heart, intestine, adipocyte, kidney, brain etc; protein designated as H-FABP indicates that it is heart type). However, expression of these isoform is not exclusive and more than one isoform can be found in a given cell or tissue. Three main types of FABPs that were initially discovered in the heart (FABP-H), liver (FABP-L), and intestine (FABP-I) are not exclusive these tissues and show considerable differences at the aa level (~30% identity). Other FABPs recently detected in adipocyte, kidney, and brain show a high degree of sequence homology among each other and with other FABPs. FABPs are also known as mammary derived growth inhibitor (MDGI), adipocyte lipid binding protein (ALBP), Myelin protein P2 homolog, P2 adipocyte protein, 422 protein (P15). Human FABP-H or adipocyte is 132aa protein (chromosome 2p11). Rat and mouse adipocyte-FABPs are 133aa single polypeptide chains.

Small volumes of anti-FABP7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS631076 is an antibody targeting FABP7. Also known as Anti-Fatty Acid Binding Protein, Heart, Adipocyte (FABP). Reactive in Human. Host: Rabbit.