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STK10 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS631146

This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of… More details

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Product Overview

Online Datasheet in PDF
Product Name
STK10, Polyclonal Antibody
Full Product Name
STK10, CT (Serine/threonine Kinase 10, Serine/threonine-protein Kinase 10, Lymphocyte-oriented Kinase, LOK, PRO2729)
Product Gene Name
Product Synonym Names
Anti -STK10, CT (Serine/threonine Kinase 10, Serine/threonine-protein Kinase 10, Lymphocyte-oriented Kinase, LOK, PRO2729)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human LOK.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
112,135 Da
Chromosome Location
Chromosome: 5; NC_000005.9 (171469074..171615346, complement). Location: 5q35.1
OMIM
603919
3D Structure
ModBase 3D Structure for O94804
Immunogen
Synthetic peptide selected from the C-terminal region of human LOK (KLH).
Applications Tested/Suitable for anti-STK10 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-STK10 antibody
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100

Western Blot (WB) of anti-STK10 antibody

The anti-LOK Pab is used in Western blot to detect LOK in Jurkat cell lysate.
Rabbit Anti-STK10 Polyclonal Antibody – Cat# MBS631146

Immunohistochemistry (IHC) of anti-STK10 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Rabbit Anti-STK10 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS631146

Other Notes

Small volumes of anti-STK10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for STK10 purchase

MBS631146 is an antibody targeting STK10. Also known as STK10, CT (Serine/threonine Kinase 10, Serine/threonine-protein Kinase 10, Lymphocyte-oriented Kinase, LOK, PRO2729). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for STK10. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
serine/threonine-protein kinase 10
NCBI Official Synonym Full Names
serine/threonine kinase 10
NCBI Official Symbol
STK10
NCBI Official Synonym Symbols
LOK; PRO2729
UniProt Protein Name
Serine/threonine-protein kinase 10
UniProt Synonym Protein Names
Lymphocyte-oriented kinase
UniProt Gene Name
STK10
UniProt Synonym Gene Names
LOK
UniProt Entry Name
STK10_HUMAN
NCBI Protein Information
serine/threonine-protein kinase 10; OTTHUMP00000223448; lymphocyte-oriented kinase

UniProt Comments for STK10

LOK: a protein kinase of the STE20 family. Highly expressed in hematopoietic tissue. May cooperate with SLK to regulate Plk1 function in human cells.

Protein type: EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, STE; STE group; STE20 family; SLK subfamily

Chromosomal Location of Human Ortholog: 5q35.1

Cellular Component: cytoplasm; plasma membrane

Molecular Function: identical protein binding; protein serine/threonine kinase activity; protein binding; protein homodimerization activity; polo kinase kinase activity; ATP binding

Biological Process: protein amino acid autophosphorylation; cell cycle; protein amino acid phosphorylation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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