Rabbit Anti-KAZ Polyclonal Antibody – Cat# MBS6312140

KAZ Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the KAZ antibody detected the KAZ protein (arrow).

KAZ Antibody – Rabbit Polyclonal

Name: KAZ Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6312140
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6312140

Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known. More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

KAZ, Polyclonal Antibody

Full Product Name

KAZ, CT (KAZN, KAZ, KIAA1026, Kazrin) (FITC)

Product Gene Name

anti-KAZ antibody

Product Synonym Names

KAZN; KAZ; KIAA1026; Kazrin

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

46,250 Da

3D Structure

ModBase 3D Structure for Q674X7

Immunogen

KAZ antibody is generated from rabbits immunized with a KLH conjugated synthetic between 710-739 amino acids selected from the C-terminal region of human KAZ.

Conjugate

FITC

Note

Preservative Free

Special Handling

Light sensitive

Product Categories/Family for anti-KAZ antibody

Antibodies; KIAA; orf

Applications Tested/Suitable for anti-KAZ antibody

Western Blot (WB), FLISA

Application Notes for anti-KAZ antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-KAZ antibody

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Nachat, R., et al. J. Cell. Sci. 122 (PT 22), 4035-4041 (2009): Wang, Q., et al. Acta Biochim. Biophys. Sin. (Shanghai) 41(9):763-772(2009). Sevilla, L.M., et al. J. Cell. Sci. 121 (PT 21), 3561-3569 (2008): Uhl, G.R., et al. Arch. Gen. Psychiatry 65(6):683-693(2008).

Other Notes

Small volumes of anti-KAZ antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KAZ purchase

MBS6312140 is an antibody targeting KAZ. Also known as KAZ, CT (KAZN, KAZ, KIAA1026, Kazrin) (FITC). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KAZ. It may not necessarily be applicable to this product.

NCBI GI #

63999741

NCBI GeneID

23254

NCBI Accession #

NP_001017999.1

UniProt Primary Accession #

Q674X7

UniProt Secondary Accession #

Q5TGF1; Q674X4; Q674X6; Q6ZUD1; Q8IYN7; Q8N409; Q9UIL2; Q9UPX4; B0QYQ0; B1AK78

UniProt Related Accession #

Q674X7

GenBank Nucleotide #

NM_001017999.2

NCBI Official Full Name

kazrin isoform C

NCBI Official Synonym Full Names

kazrin, periplakin interacting protein

NCBI Official Symbol

KAZN

NCBI Official Synonym Symbols

KAZ

UniProt Protein Name

Kazrin

Protein Family

Kazal-type serine protease inhibitor domain-containing protein

UniProt Gene Name

KAZN

UniProt Synonym Gene Names

KAZ; KIAA1026

UniProt Entry Name

KAZRN_HUMAN

NCBI Protein Information

kazrin

NCBI Summary for KAZ

This gene encodes a protein that plays a role in desmosome assembly, cell adhesion, cytoskeletal organization, and epidermal differentiation. This protein co-localizes with desmoplakin and the cytolinker protein periplakin. In general, this protein localizes to the nucleus, desmosomes, cell membrane, and cortical actin-based structures. Some isoforms of this protein also associate with microtubules. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity has not been verified. [provided by RefSeq, Aug 2011]

Research Articles on KAZ

1. exons 5-15 of kazrin, encoding the nuclear localization signal and C-terminal domain, are not required for epidermal development and function

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-KAZ antibody

Disease Name	Pubmed Publications
Pain Antibodies	>1 publications with KAZ and Pain

Organs/Tissues associated with anti-KAZ antibody

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>3 publications with KAZ and Bone
Muscle Antibodies	>3 publications with KAZ and Muscle
Blood Antibodies	>1 publications with KAZ and Blood