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KCNG3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6312431

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal… More details

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Product Overview

Online Datasheet in PDF
Product Name
KCNG3, Polyclonal Antibody
Full Product Name
KCNG3, NT (KCNG3, Potassium voltage-gated channel subfamily G member 3, Voltage-gated potassium channel subunit Kv10.1, Voltage-gated potassium channel subunit Kv6.3) (MaxLight 650)
Product Gene Name
Product Synonym Names
KCNG3; Potassium voltage-gated channel subfamily G member 3; Voltage-gated potassium channel subunit Kv10.1; Voltage-gated potassium channel subunit Kv6.3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
49,593 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (42669157..42721237, complement). Location: 2p21
OMIM
606767
3D Structure
ModBase 3D Structure for Q8TAE7
Immunogen
KCNG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between amino acid 15-45 from the N-terminal region of human KCNG3.
Conjugate
MaxLight650
Note
Preservative Free

Product Categories/Family for anti-KCNG3 antibody

Applications Tested/Suitable for anti-KCNG3 antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes for anti-KCNG3 antibody
IHC: 1:50-100
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.

Product References and Citations for anti-KCNG3 antibody

Mederos Y Schnitzler, M., et al. J. Biol. Chem. 284(7):4695-4704(2009). Gutman, G.A., et al. Pharmacol. Rev. 57(4):473-508(2005). Vega-Saenz de Miera, E.C. Brain Res. Mol. Brain Res. 123 (1-2), 91-103 (2004).

Other Notes

Small volumes of anti-KCNG3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KCNG3 purchase

MBS6312431 is an antibody targeting KCNG3. Also known as KCNG3, NT (KCNG3, Potassium voltage-gated channel subfamily G member 3, Voltage-gated potassium channel subunit Kv10.1, Voltage-gated potassium channel subunit Kv6.3) (MaxLight 650). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KCNG3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
potassium voltage-gated channel subfamily G member 3 isoform 1
NCBI Official Synonym Full Names
potassium voltage-gated channel, subfamily G, member 3
NCBI Official Symbol
KCNG3
NCBI Official Synonym Symbols
KV6.3; KV10.1
UniProt Protein Name
Potassium voltage-gated channel subfamily G member 3
UniProt Synonym Protein Names
Voltage-gated potassium channel subunit Kv10.1; Voltage-gated potassium channel subunit Kv6.3
UniProt Gene Name
KCNG3
UniProt Entry Name
KCNG3_HUMAN
NCBI Protein Information
potassium voltage-gated channel subfamily G member 3; voltage-gated potassium channel 6.3; voltage-gated potassium channel Kv10.1; voltage-gated potassium channel subunit Kv6.3; voltage-gated potassium channel subunit Kv6.4; voltage-gated potassium channe

NCBI Summary for KCNG3

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit functioning as a modulatory molecule. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
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UniProt Comments for KCNG3

KCNG3: Potassium channel subunit. Modulates channel activity. Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.3/KCNG3 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 2p21

Cellular Component: voltage-gated potassium channel complex; endoplasmic reticulum; integral to membrane; plasma membrane

Molecular Function: protein binding; delayed rectifier potassium channel activity

Biological Process: synaptic transmission; protein homooligomerization
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KCNG3 antibody

Organs/Tissues associated with anti-KCNG3 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with KCNG3 and Brain
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