Rabbit Anti-KCNIP4 Polyclonal Antibody – Cat# MBS6312470

KCNIP4 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the KCNIP4 antibody detected the KCNIP4 protein (arrow).

KCNIP4 Antibody – Rabbit Polyclonal

Name: KCNIP4 Antibody; Polyclonal; Rabbit; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6312470
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6312470

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

KCNIP4, Polyclonal Antibody

Full Product Name

KCNIP4, NT (KCNIP4, CALP, KCHIP4, Kv channel-interacting protein 4, A-type potassium channel modulatory protein 4, Calsenilin-like protein, Potassium channel-interacting protein 4) (FITC)

Product Gene Name

anti-KCNIP4 antibody

Product Synonym Names

KCNIP4; CALP; KCHIP4; Kv channel-interacting protein 4; A-type potassium channel modulatory protein 4; Calsenilin-like protein; Potassium channel-interacting protein 4

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

28,729 Da

Chromosome Location

Chromosome: 4; NC_000004.11 (20730234..21950424, complement). Location: 4p15.32

3D Structure

ModBase 3D Structure for Q6PIL6

Immunogen

KCNIP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-39 amino acids from the N-terminal region of human KCNIP4.

Conjugate

FITC

Note

Preservative Free

Special Handling

Light sensitive

Product Categories/Family for anti-KCNIP4 antibody

Antibodies; Ion Channel

Applications Tested/Suitable for anti-KCNIP4 antibody

Western Blot (WB), FLISA

Application Notes for anti-KCNIP4 antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-KCNIP4 antibody

Horinouchi, M., et al. Pediatr Hematol Oncol 27(5):344-354(2010). Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Lin, L., et al. Mol. Cell. Neurosci. 43(3):315-325(2010). Ding, H., et al. Stroke 41(1):177-180(2010). Trynka, G., et al. Gut 58(8):1078-1083(2009).

Other Notes

Small volumes of anti-KCNIP4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KCNIP4 purchase

MBS6312470 is an antibody targeting KCNIP4. Also known as KCNIP4, NT (KCNIP4, CALP, KCHIP4, Kv channel-interacting protein 4, A-type potassium channel modulatory protein 4, Calsenilin-like protein, Potassium channel-interacting protein 4) (FITC). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KCNIP4. It may not necessarily be applicable to this product.

NCBI GI #

78190488

NCBI GeneID

80333

NCBI Accession #

NP_001030176.1

NCBI Related Accession #

NP_079497.2

UniProt Primary Accession #

Q6PIL6

UniProt Secondary Accession #

Q3YAB8; Q3YAB9; Q3YAC0; Q3YAC1; Q3YAC2; Q4W5G8; Q8NEU0; Q9BWT2; Q9H294; Q9H2A4

UniProt Related Accession #

Q6PIL6

GenBank Nucleotide #

NM_001035004.1

NCBI Official Full Name

Kv channel-interacting protein 4 isoform 3

NCBI Official Synonym Full Names

Kv channel interacting protein 4

NCBI Official Symbol

KCNIP4

NCBI Official Synonym Symbols

CALP; KCHIP4

UniProt Protein Name

Kv channel-interacting protein 4

UniProt Synonym Protein Names

A-type potassium channel modulatory protein 4; Calsenilin-like protein1 PublicationManual assertion based on opinion iniRef.1"Molecular cloning and characterization of CALP/KChIP4, a novel EF-hand protein interacting with presenilin 2 and voltage-gated potassium channel subunit Kv4."Morohashi Y., Hatano N., Ohya S., Takikawa R., Watabiki T., Takasugi N., Imaizumi Y., Tomita T., Iwatsubo T.J. Biol. Chem. 277:14965-14975(2002) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INTERACTION WITH KCND2; PSEN1 AND PSEN2, CALCIUM-BINDING.

Protein Family

Kv channel-interacting protein

UniProt Gene Name

KCNIP4

UniProt Synonym Gene Names

CALP; KCHIP4; KChIP4

NCBI Protein Information

Kv channel-interacting protein 4; calsenilin-like protein; potassium channel interacting protein 4; potassium channel-interacting protein 4; a-type potassium channel modulatory protein 4

UniProt Comments for KCNIP4

Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner (PubMed:11847232, PubMed:18957440, PubMed:23576435). Modulates KCND3/Kv4.3 currents (PubMed:23576435). Isoform 4 does not increase KCND2 expression at the cell membrane (PubMed:18957440). Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane.

Research Articles on KCNIP4

1. Genome-wide association study identifies KCNIP4 as an asthma gene in human and in mouse.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KCNIP4 antibody

Reference Product	PubMed Publications
KCNIP2 antibody	>5 publications with KCNIP4 and KCNIP2
KCND2 antibody	>4 publications with KCNIP4 and KCND2
KCND3 antibody	>2 publications with KCNIP4 and KCND3
CTNNB1 antibody	>2 publications with KCNIP4 and CTNNB1
LEF1 antibody	>1 publications with KCNIP4 and LEF1
PSEN2 antibody	>1 publications with KCNIP4 and PSEN2

Pathways associated with anti-KCNIP4 antibody

Products by Pathway	Pathway Diagram
Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway antibodies	Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway Diagram

Diseases associated with anti-KCNIP4 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>3 publications with KCNIP4 and Neoplasms
Nervous System Diseases Antibodies	>2 publications with KCNIP4 and Nervous System Diseases
Nerve Degeneration Antibodies	>1 publications with KCNIP4 and Nerve Degeneration
Adenocarcinoma Antibodies	>1 publications with KCNIP4 and Adenocarcinoma
Kidney Diseases Antibodies	>1 publications with KCNIP4 and Kidney Diseases
Drug-Induced Liver Injury Antibodies	>1 publications with KCNIP4 and Drug-Induced Liver Injury

Organs/Tissues associated with anti-KCNIP4 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>10 publications with KCNIP4 and Brain
Nerve Antibodies	>2 publications with KCNIP4 and Nerve
Liver Antibodies	>1 publications with KCNIP4 and Liver
Kidney Antibodies	>1 publications with KCNIP4 and Kidney