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KIR2DS2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6313412

MBS6313412 is an antibody targeting KIR2DS2. Also known as KIR2DS2, ID (KIR2DS2, CD158J, NKAT5, Killer cell immunoglobulin-like receptor 2DS2, CD158 antigen-like family member J, MHC class I NK cell receptor, NK receptor 183 ActI, Natural killer-associated… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KIR2DS2, Polyclonal Antibody
Full Product Name
KIR2DS2, ID (KIR2DS2, CD158J, NKAT5, Killer cell immunoglobulin-like receptor 2DS2, CD158 antigen-like family member J, MHC class I NK cell receptor, NK receptor 183 ActI, Natural killer-associated transcript 5, p58 natural killer cell receptor clone CL-4
Product Gene Name
Product Synonym Names
KIR2DS2; CD158J; NKAT5; Killer cell immunoglobulin-like receptor 2DS2; CD158 antigen-like family member J; MHC class I NK cell receptor; NK receptor 183 ActI; Natural killer-associated transcript 5; p58 natural killer cell receptor clone CL-49; CD158j
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified by Protein A and Peptide Affinity Chromatography.
Specificity
Recognizes human KIR2DS2.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
33,502 Da
OMIM
604953
3D Structure
ModBase 3D Structure for P43631
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 39-65 in the central region of human KIR2DS2.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-KIR2DS2 antibody

Applications Tested/Suitable for anti-KIR2DS2 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), Flow Cytometry (FC/FACS), FLISA
Application Notes for anti-KIR2DS2 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-KIR2DS2 antibody

Western Blot analysis in A2058 cell line lysates (35ug/lane) usingMBS642788. This demonstrates that MBS642788 detected the KIR2DS2 protein (arrow).
Rabbit Anti-KIR2DS2 Polyclonal Antibody – Cat# MBS6313412

Immunohistochemistry (IHC) of anti-KIR2DS2 antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma using MBS642788 followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of MBS642788 for immunohistochemistry.
Rabbit Anti-KIR2DS2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6313412

Flow Cytometry (FC/FACS) of anti-KIR2DS2 antibody

Flow Cytometry analysis of A2058 cells using MBS642788 (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-KIR2DS2 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS6313412

Product References and Citations for anti-KIR2DS2 antibody

1. Biassoni, R., et al. J. Exp. Med. 183(2):645-650(1996). 2. Dohring, C., et al. Immunogenetics 44(3):227-230(1996). 3. Wagtmann, N., et al. Immunity 2(5):439-449(1995). 4. Colonna, M., et al. Science 268(5209):405-408(1995).

Other Notes

Small volumes of anti-KIR2DS2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KIR2DS2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
killer cell immunoglobulin-like receptor 2DS2 isoform a
NCBI Official Synonym Full Names
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
NCBI Official Symbol
KIR2DS2
NCBI Official Synonym Symbols
NKAT5; cl-49; CD158J; CD158b; NKAT-5; 183ActI
UniProt Protein Name
Killer cell immunoglobulin-like receptor 2DS2
UniProt Synonym Protein Names
CD158 antigen-like family member J; MHC class I NK cell receptor; NK receptor 183 ActI; Natural killer-associated transcript 5; NKAT-5; p58 natural killer cell receptor clone CL-49; p58 NK receptor CL-49; CD_antigen: CD158j
UniProt Gene Name
KIR2DS2
UniProt Synonym Gene Names
CD158J; NKAT5; NKAT-5; p58 NK receptor CL-49
UniProt Entry Name
KI2S2_HUMAN
NCBI Protein Information
killer cell immunoglobulin-like receptor 2DS2; NK receptor 183 ActI; MHC class I NK cell receptor; killer-cell Ig-like receptor; CD158 antigen-like family member J; natural killer associated transcript 5; natural killer cell inhibitory receptor; p58 kille

UniProt Comments for KIR2DS2

KIR2DS2: Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells. Belongs to the immunoglobulin superfamily.

Chromosomal Location of Human Ortholog: 19q13.4

Cellular Component: integral to membrane; plasma membrane

Molecular Function: transmembrane receptor activity

Biological Process: immune response; innate immune response; regulation of immune response; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KIR2DS2 antibody

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