Mouse Anti-ATP6AP1 Monoclonal Antibody – Cat# MBS631437

Atpase H+ Transporting Lysosomal Accessory Protein 1 (ATP6AP1) Antibody – Mouse Monoclonal

Name: ATP6AP1 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS631437
Price: 880 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS631437

This gene encodes a component of a multisubunit enzyme (1mD MW) that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain.… More details

$880 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ATPase H+ Transporting Lysosomal Accessory Protein 1 (ATP6AP1), Monoclonal Antibody

Full Product Name

ATPase H+ Transporting Lysosomal Accessory Protein 1 (ATP6AP1, 16A, Ac45, ATPase H+ Transporting Lysosomal (Vacuolar Proton Pump) Subunit 1, ATP6S1, ATPase H+ Transporting Lysosomal Interacting Protein 1, ATP6IP1, CF2, H-ATPase Subunit, MGC129781, Protein

Product Gene Name

anti-ATP6AP1 antibody

Product Synonym Names

Anti -ATPase H+ Transporting Lysosomal Accessory Protein 1 (ATP6AP1, 16A, Ac45, ATPase H+ Transporting Lysosomal (Vacuolar Proton Pump) Subunit 1, ATP6S1, ATPase H+ Transporting Lysosomal Interacting Protein 1, ATP6IP1, CF2, H-ATPase Subunit, MGC129781, Protein

Clonality

Monoclonal

Isotype

IgG1,k

Clone Number

10B237

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human ATP6AP1.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

52,026 Da

Chromosome Location

Chromosome: X; NC_000023.10 (153656978..153664862). Location: Xq28

OMIM

300197

3D Structure

ModBase 3D Structure for Q15904

Immunogen

Partial recombinant protein corresponding to a portion of aa51-151 of human ATP6AP1 (NP_001174), with GST tag. MW of GST tag alone is 26kD.

Product Categories/Family for anti-ATP6AP1 antibody

Antibodies; Abs to Enzymes; Synthase

Applications Tested/Suitable for anti-ATP6AP1 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-ATP6AP1 antibody

Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1:500-1:1000
ELISA: 3ng/ml-1ug/ml

Other Notes

Small volumes of anti-ATP6AP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ATP6AP1 purchase

MBS631437 is an antibody targeting ATP6AP1. Also known as ATPase H+ Transporting Lysosomal Accessory Protein 1 (ATP6AP1, 16A, Ac45, ATPase H+ Transporting Lysosomal (Vacuolar Proton Pump) Subunit 1, ATP6S1, ATPase H+ Transporting Lysosomal Interacting Protein 1, ATP6IP1, CF2, H-ATPase Subunit, MGC129781, Protein. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ATP6AP1. It may not necessarily be applicable to this product.

NCBI GI #

119593120

NCBI GeneID

537

UniProt Primary Accession #

Q15904

UniProt Secondary Accession #

A6ZKI4

UniProt Related Accession #

Q15904; Q8NBT4; Q8NF19; Q9H0C7

NCBI Official Full Name

ATPase, H+ transporting, lysosomal accessory protein 1, isoform CRA_c

NCBI Official Synonym Full Names

ATPase, H+ transporting, lysosomal accessory protein 1

NCBI Official Symbol

ATP6AP1

NCBI Official Synonym Symbols

16A; CF2; Ac45; XAP3; XAP-3; ATP6S1; VATPS1; ATP6IP1; MGC129781

UniProt Protein Name

V-type proton ATPase subunit S1

UniProt Synonym Protein Names

Protein XAP-3; V-ATPase Ac45 subunit; V-ATPase S1 accessory protein; Vacuolar proton pump subunit S1

Protein Family

V-type proton ATPase

UniProt Gene Name

ATP6AP1

UniProt Synonym Gene Names

ATP6IP1; ATP6S1; VATPS1; XAP3

UniProt Entry Name

VAS1_HUMAN

NCBI Protein Information

V-type proton ATPase subunit S1; protein XAP-3; H-ATPase subunit; OTTHUMP00000032115; OTTHUMP00000196463; V-ATPase subunit S1; V-ATPase Ac45 subunit; V-ATPase S1 accessory protein; vacuolar proton pump subunit S1; ATPase, H+ transporting, lysosomal interacting protein 1; ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit 1

NCBI Summary for ATP6AP1

This gene encodes a component of a multisubunit enzyme (1 mDa MW) that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene is approximately 45 kD and may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. [provided by RefSeq]

UniProt Comments for ATP6AP1

ATP6AP1: Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Belongs to the vacuolar ATPase subunit S1 family.

Protein type: Energy Metabolism - oxidative phosphorylation; Membrane protein, integral; Hydrolase; Transporter; EC 3.6.3.14

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: vacuolar membrane; integral to membrane; endosome membrane; proton-transporting two-sector ATPase complex

Molecular Function: transporter activity; hydrogen ion transporting ATP synthase activity, rotational mechanism; hydrogen ion transporting ATPase activity, rotational mechanism; ATP binding; Rab GTPase binding

Biological Process: positive regulation of osteoblast differentiation; proton transport; cellular iron ion homeostasis; pH reduction; ATP hydrolysis coupled proton transport; insulin receptor signaling pathway; transferrin transport; positive regulation of bone resorption; transmembrane transport; positive regulation of exocytosis; establishment of organelle localization

Research Articles on ATP6AP1

1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ATP6AP1 antibody

Products by Pathway	Pathway Diagram
Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway antibodies	Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway Diagram
Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway antibodies	Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway Diagram
Lysosome Pathway antibodies	Lysosome Pathway Diagram
Lysosome Pathway antibodies	Lysosome Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Oxidative Phosphorylation Pathway antibodies	Oxidative Phosphorylation Pathway Diagram
Oxidative Phosphorylation Pathway antibodies	Oxidative Phosphorylation Pathway Diagram
Oxidative Phosphorylation Pathway antibodies	Oxidative Phosphorylation Pathway Diagram
Phagosome Pathway antibodies	Phagosome Pathway Diagram
Phagosome Pathway antibodies	Phagosome Pathway Diagram

Diseases associated with anti-ATP6AP1 antibody

Disease Name	Pubmed Publications
Bone Resorption Antibodies	>8 publications with ATP6AP1 and Bone Resorption
Bone Diseases, Developmental Antibodies	>6 publications with ATP6AP1 and Bone Diseases, Developmental
Osteoporosis Antibodies	>3 publications with ATP6AP1 and Osteoporosis
Retinal Degeneration Antibodies	>2 publications with ATP6AP1 and Retinal Degeneration
Breast Neoplasms Antibodies	>1 publications with ATP6AP1 and Breast Neoplasms
Ovarian Neoplasms Antibodies	>1 publications with ATP6AP1 and Ovarian Neoplasms
Adenoma Antibodies	>1 publications with ATP6AP1 and Adenoma
Pancreatic Neoplasms Antibodies	>1 publications with ATP6AP1 and Pancreatic Neoplasms
Fetal Diseases Antibodies	>1 publications with ATP6AP1 and Fetal Diseases
Ovarian Diseases Antibodies	>1 publications with ATP6AP1 and Ovarian Diseases

Organs/Tissues associated with anti-ATP6AP1 antibody

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>8 publications with ATP6AP1 and Bone
Blood Antibodies	>4 publications with ATP6AP1 and Blood
Eye Antibodies	>3 publications with ATP6AP1 and Eye
Nerve Antibodies	>3 publications with ATP6AP1 and Nerve
Bone Marrow Antibodies	>2 publications with ATP6AP1 and Bone Marrow
Embryonic Tissue Antibodies	>2 publications with ATP6AP1 and Embryonic Tissue
Liver Antibodies	>2 publications with ATP6AP1 and Liver
Pancreas Antibodies	>2 publications with ATP6AP1 and Pancreas
Kidney Antibodies	>2 publications with ATP6AP1 and Kidney
Brain Antibodies	>2 publications with ATP6AP1 and Brain