• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Serotonin Receptor 1a (HTR1A) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS631575

Serotonin Receptor 1A, also known as 5-hydroxytryptamine receptor 1A, is a member of the G protein-coupled receptor family. Serotonin Receptor 1A has been found to be expressed highly in the septum and hippocampus. Serotonin Receptor 1A seems to have an… More details

$1045 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Serotonin Receptor 1A (HTR1A), Monoclonal Antibody
Full Product Name
Serotonin Receptor 1A
Product Gene Name
Product Synonym Names
Anti -Serotonin Receptor 1A
Clonality
Monoclonal
Isotype
IgM,k
Clone Number
11C254
Host
Mouse
Species Reactivity
Human, Rat
Form/Format
Supplied as a liquid in PBS, 0.05% sodium azide.
Purity/Purification
Highly Purified
Purified by ion exchange chromatography.
Specificity
Recognizes rat Seratonin receptor 1A. Species Crossreactivity: human.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
46,356 Da
Chromosome Location
Chromosome: 2; NC_006584.2 (52876052..52877323, complement)
3D Structure
ModBase 3D Structure for Q6XXX9
Immunogen
Linear peptide corresponding to rat Serotonin Receptor 1A, conjugated to KLH (NP_036717).
Positive Control
Rat brain tissue lysate
Applications Tested/Suitable for anti-HTR1A antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-HTR1A antibody
Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Western Blot: 0.5ug/ml detects Serotonin Receptor 1A on 10ug of rat brain tissue lysate. Band is observed at ~40kD. Calculated MW is 46kD.
Immunohistochemistry: 1:400 detects Serotonin Receptor 1A in normal human brain tissue.

Western Blot (WB) of anti-HTR1A antibody

Western Blot: Rat brain tissue lysate was probed with MBS631575 at 0.5ug/ml. Proteins were visualized using a goat anti-mouse IgM secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates Serotonin Receptor 1A (~40kD).
Mouse Anti-HTR1A Monoclonal Antibody – Cat# MBS631575

Immunohistochemistry (IHC) of anti-HTR1A antibody

Immunohistochemistry Analysis: Paraffin-embedded normal human brain tissue was prepared using heat-induced epitope retrieval in citrate buffer, pH 6.0. Immunostaining was performed using a 1:400 dilution of MBS631575 Reactivity was detected using the a detection kit. Staining pattern appears as cytoplasmic.
Mouse Anti-HTR1A Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS631575

Other Notes

Small volumes of anti-HTR1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HTR1A purchase

MBS631575 is an antibody targeting HTR1A. Also known as Serotonin Receptor 1A. Reactive in Human, Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for HTR1A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
serotonin receptor 1A
NCBI Official Symbol
HTR1A
UniProt Protein Name
5-hydroxytryptamine receptor 1A
UniProt Synonym Protein Names
Serotonin receptor 1A
UniProt Gene Name
HTR1A
UniProt Entry Name
5HT1A_CANFA
NCBI Protein Information
5-hydroxytryptamine receptor 1A; 5-HT-1A; 5-HT1A receptor; serotonin receptor 1A

UniProt Comments for HTR1A

Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity

Subcellular location: Cell membrane; Multi-pass membrane protein.

Sequence similarities: Belongs to the G-protein coupled receptor 1 family. 5-hydroxytryptamine receptor subfamily. HTR1A sub-subfamily.
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000