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LGI3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6315867

MBS6315867 is an antibody targeting LGI3. Also known as LGI3, ID (LGI3, LGIL4, Leucine-rich repeat LGI family member 3, LGI1-like protein 4, Leucine-rich glioma-inactivated protein 3) (APC). Reactive in Human. Host: Rabbit. LGI3 may participate in the… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
LGI3, Polyclonal Antibody
Full Product Name
LGI3, ID (LGI3, LGIL4, Leucine-rich repeat LGI family member 3, LGI1-like protein 4, Leucine-rich glioma-inactivated protein 3) (APC)
Product Gene Name
Product Synonym Names
LGI3; LGIL4; Leucine-rich repeat LGI family member 3; LGI1-like protein 4; Leucine-rich glioma-inactivated protein 3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
58,871 Da
OMIM
608302
3D Structure
ModBase 3D Structure for Q8N145
Immunogen
LGI3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 310-338 amino acids from the Central region of human LGI3.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive
Applications Tested/Suitable for anti-LGI3 antibody
Western Blot (WB), FLISA
Application Notes for anti-LGI3 antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-LGI3 antibody

LGI3 Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the LGI3 antibody detected the LGI3 protein (arrow).
Rabbit Anti-LGI3 Polyclonal Antibody – Cat# MBS6315867

Product References and Citations for anti-LGI3 antibody

Okabayashi, S., et al. Neuroreport 19(12):1175-1179(2008). Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003). Staub, E., et al. Trends Biochem. Sci. 27(9):441-444(2002). Scheel, H., et al. Hum. Mol. Genet. 11(15):1757-1762(2002). Gu, W., et al. FEBS Lett. 519 (1-3), 71-76 (2002).

Other Notes

Small volumes of anti-LGI3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LGI3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
leucine-rich repeat LGI family member 3
NCBI Official Synonym Full Names
leucine-rich repeat LGI family, member 3
NCBI Official Symbol
LGI3
NCBI Official Synonym Symbols
LGIL4
UniProt Protein Name
Leucine-rich repeat LGI family member 3
UniProt Synonym Protein Names
LGI1-like protein 4; Leucine-rich glioma-inactivated protein 3
UniProt Gene Name
LGI3
UniProt Synonym Gene Names
LGIL4
UniProt Entry Name
LGI3_HUMAN
NCBI Protein Information
leucine-rich repeat LGI family member 3; LGI1-like protein 4; leucine-rich glioma-inactivated protein 3

UniProt Comments for LGI3

LGI3: May participate in the regulation of neuronal exocytosis.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 8p21.3

Cellular Component: synaptic vesicle; neuron projection; extracellular region; cell junction

Molecular Function: catalytic activity

Biological Process: regulation of exocytosis; exocytosis; metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-LGI3 antibody

Organs/Tissues associated with anti-LGI3 antibody

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