Rabbit Anti-LIPT2 Polyclonal Antibody – Cat# MBS6316471

LIPT2 Antibody (N-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the LIPT2 antibody detected the LIPT2 protein (arrow).

LIPT2 Antibody – Rabbit Polyclonal

Name: LIPT2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6316471
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6316471

LIPT2 catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LIPT2, Polyclonal Antibody

Full Product Name

LIPT2, NT (LIPT2, Putative lipoyltransferase 2, mitochondrial, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase) (AP)

Product Gene Name

anti-LIPT2 antibody

Product Synonym Names

LIPT2; Putative lipoyltransferase 2, mitochondrial; Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

25,195 Da

OMIM

617659

3D Structure

ModBase 3D Structure for A6NK58

Immunogen

LIPT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-43 amino acids from the N-terminal region of human LIPT2.

Conjugate

Note

Preservative Free

Product Categories/Family for anti-LIPT2 antibody

Antibodies; Mitochondrial Proteins

Applications Tested/Suitable for anti-LIPT2 antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-LIPT2 antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-LIPT2 antibody

Venter, J.C., et al. Science 291(5507):1304-1351(2001).

Other Notes

Small volumes of anti-LIPT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LIPT2 purchase

MBS6316471 is an antibody targeting LIPT2. Also known as LIPT2, NT (LIPT2, Putative lipoyltransferase 2, mitochondrial, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase) (AP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LIPT2. It may not necessarily be applicable to this product.

NCBI GI #

221554520

NCBI GeneID

387787

NCBI Accession #

NP_001138341.1

UniProt Primary Accession #

A6NK58

UniProt Related Accession #

A6NK58

GenBank Nucleotide #

NM_001144869.2

NCBI Official Full Name

putative lipoyltransferase 2, mitochondrial isoform 1

NCBI Official Synonym Full Names

lipoyl(octanoyl) transferase 2

NCBI Official Symbol

LIPT2

UniProt Protein Name

Putative lipoyltransferase 2, mitochondrial

UniProt Synonym Protein Names

Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase

Protein Family

Putative lipoyltransferase

UniProt Gene Name

LIPT2

NCBI Protein Information

putative lipoyltransferase 2, mitochondrial

NCBI Summary for LIPT2

This gene encodes a mitochondrial protein that catalyzes the transfer of octanoic acid to lipoate-dependent enzymes such as octanoyl-ACP. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]

UniProt Comments for LIPT2

Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes, which catalyze essential redox reactions (PubMed:28757203). Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate ().

Research Articles on LIPT2

1. The authors report on the identification of biallelic LIPT2 mutations in three affected individuals from two families with severe neonatal encephalopathy where a normalization of lipoylation was observed after expression of wild-type LIPT2, arguing for LIPT2 requirement in intramitochondrial lipoate synthesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LIPT2 antibody

Reference Product	PubMed Publications
LIPT1 antibody	>1 publications with LIPT2 and LIPT1
LIAS antibody	>1 publications with LIPT2 and LIAS

Pathways associated with anti-LIPT2 antibody

Products by Pathway	Pathway Diagram
Lipoic Acid Metabolism Pathway antibodies	Lipoic Acid Metabolism Pathway Diagram
Lipoic Acid Metabolism Pathway antibodies	Lipoic Acid Metabolism Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram

Diseases associated with anti-LIPT2 antibody

Disease Name	Pubmed Publications
Death Antibodies	>1 publications with LIPT2 and Death