Rabbit Anti-LMO2 Polyclonal Antibody – Cat# MBS6316587

LMO2 Antibody – Rabbit Polyclonal

Name: LMO2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6316587
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6316587

LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately… More details

$1060 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LMO2, Polyclonal Antibody

Full Product Name

LMO2, NT (LMO2, RBTN2, RBTNL1, RHOM2, TTG2, Rhombotin-2, Cysteine-rich protein TTG-2, LIM domain only protein 2, T-cell translocation protein 2) (MaxLight 490)

Product Gene Name

anti-LMO2 antibody

Product Synonym Names

LMO2; RBTN2; RBTNL1; RHOM2; TTG2; Rhombotin-2; Cysteine-rich protein TTG-2; LIM domain only protein 2; T-cell translocation protein 2

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

OMIM

180385

3D Structure

ModBase 3D Structure for P25791

Immunogen

LMO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human LMO2.

Conjugate

MaxLight490

Note

Preservative Free

Product Categories/Family for anti-LMO2 antibody

Antibodies; Amino Acids

Applications Tested/Suitable for anti-LMO2 antibody

Immunohistochemistry (IHC), FLISA, Western Blot (WB)

Application Notes for anti-LMO2 antibody

IHC: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.

Product References and Citations for anti-LMO2 antibody

Oram, S.H., et al. Oncogene 29(43):5796-5808(2010). Younes, S.F., et al. Am. J. Surg. Pathol. 34(9):1266-1276(2010). Hirose, K., et al. Blood 116(6):962-970(2010). Durnick, D.K., et al. Am. J. Clin. Pathol. 134(2):278-281(2010). Cobanoglu, U., et al. Hematology 15(3):132-134(2010).

Other Notes

Small volumes of anti-LMO2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LMO2 purchase

MBS6316587 is an antibody targeting LMO2. Also known as LMO2, NT (LMO2, RBTN2, RBTNL1, RHOM2, TTG2, Rhombotin-2, Cysteine-rich protein TTG-2, LIM domain only protein 2, T-cell translocation protein 2) (MaxLight 490). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LMO2. It may not necessarily be applicable to this product.

NCBI GI #

214832219

NCBI GeneID

4005

NCBI Accession #

NP_001135788.1

NCBI Related Accession #

NP_001135787.1; NP_005565.2

UniProt Primary Accession #

P25791

UniProt Related Accession #

P25791

GenBank Nucleotide #

NP_001135788.1

NCBI Official Full Name

rhombotin-2 isoform 2

NCBI Official Synonym Full Names

LIM domain only 2

NCBI Official Symbol

LMO2

NCBI Official Synonym Symbols

TTG2; LMO-2; RBTN2; RHOM2; RBTNL1

UniProt Protein Name

Rhombotin-2

UniProt Synonym Protein Names

Cysteine-rich protein TTG-2; LIM domain only protein 2; LMO-2; T-cell translocation protein 2

Protein Family

Rhombotin

UniProt Gene Name

LMO2

UniProt Synonym Gene Names

RBTN2; RBTNL1; RHOM2; TTG2; LMO-2

UniProt Entry Name

RBTN2_HUMAN

NCBI Protein Information

rhombotin-2

UniProt Comments for LMO2

LMO2: Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state. A chromosomal aberration involving LMO2 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(11,14)(p13;q11) with TCRD. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; Oncoprotein

Chromosomal Location of Human Ortholog: 11p13

Cellular Component: transcription factor complex; nucleus

Molecular Function: protein binding; zinc ion binding; bHLH transcription factor binding; chromatin binding; cofactor binding

Biological Process: negative regulation of erythrocyte differentiation; embryonic hemopoiesis; multicellular organismal development; positive regulation of transcription from RNA polymerase II promoter; mRNA transcription from RNA polymerase II promoter

Research Articles on LMO2

1. Lysine deacetylation of LMO2 is essential for the LDB1 interaction and transcriptional activity of the TAL1 complex.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.