Rabbit Anti-LPAR4 Polyclonal Antibody – Cat# MBS6316782

LPAR4 Antibody (Center) western blot analysis in MDA-MB468 cell line lysates (35ug/lane).This demonstrates the LPAR4 antibody detected the LPAR4 protein (arrow).

LPAR4 Antibody – Rabbit Polyclonal

Name: LPAR4 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6316782
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6316782

This gene encodes a member of the lysophosphatidic acid receptor family. It may also be related to the P2Y receptors, a family of receptors that bind purine and pyrimidine nucleotides and are coupled to G proteins. The encoded protein may play a role in… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LPAR4, Polyclonal Antibody

Full Product Name

LPAR4, ID (LPAR4, GPR23, LPA4, P2RY9, Lysophosphatidic acid receptor 4, G-protein coupled receptor 23, P2Y purinoceptor 9, P2Y5-like receptor, Purinergic receptor 9) (FITC)

Product Gene Name

anti-LPAR4 antibody

Product Synonym Names

LPAR4; GPR23; LPA4; P2RY9; Lysophosphatidic acid receptor 4; G-protein coupled receptor 23; P2Y purinoceptor 9; P2Y5-like receptor; Purinergic receptor 9

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

41,895 Da

OMIM

300086

3D Structure

ModBase 3D Structure for Q99677

Immunogen

LPAR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-156 amino acids from the Central region of human LPAR4.

Conjugate

FITC

Note

Preservative Free

Special Handling

Light sensitive

Product Categories/Family for anti-LPAR4 antibody

Antibodies; G Protein Receptors

Applications Tested/Suitable for anti-LPAR4 antibody

Western Blot (WB), FLISA

Application Notes for anti-LPAR4 antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-LPAR4 antibody

Liu, Y.B., et al. J. Cell. Biochem. 109(4):794-800(2010). Kumar, S.A., et al. Leuk. Lymphoma 50(12):2038-2048(2009). Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008). Dowal, L., et al. J. Biol. Chem. 281(33):23999-24014(2006). Noguchi, K., et al. J. Biol. Chem. 278(28):25600-25606(2003).

Other Notes

Small volumes of anti-LPAR4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LPAR4 purchase

MBS6316782 is an antibody targeting LPAR4. Also known as LPAR4, ID (LPAR4, GPR23, LPA4, P2RY9, Lysophosphatidic acid receptor 4, G-protein coupled receptor 23, P2Y purinoceptor 9, P2Y5-like receptor, Purinergic receptor 9) (FITC). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LPAR4. It may not necessarily be applicable to this product.

NCBI GI #

4885311

NCBI GeneID

2846

NCBI Accession #

NP_005287.1

UniProt Primary Accession #

Q99677

UniProt Secondary Accession #

O15132; Q502U9; Q6NSP5; B2RAC7

UniProt Related Accession #

Q99677

GenBank Nucleotide #

NM_005296.2

NCBI Official Full Name

lysophosphatidic acid receptor 4

NCBI Official Synonym Full Names

lysophosphatidic acid receptor 4

NCBI Official Symbol

LPAR4

NCBI Official Synonym Symbols

LPA4; P2Y9; GPR23; P2RY9; P2Y5-LIKE

UniProt Protein Name

Lysophosphatidic acid receptor 4

UniProt Synonym Protein Names

G-protein coupled receptor 23; P2Y purinoceptor 9; P2Y9; P2Y5-like receptor; Purinergic receptor 9

Protein Family

Lysophosphatidic acid receptor

UniProt Gene Name

LPAR4

UniProt Synonym Gene Names

GPR23; LPA4; P2RY9; LPA receptor 4; LPA-4; P2Y9

UniProt Entry Name

LPAR4_HUMAN

NCBI Protein Information

lysophosphatidic acid receptor 4; LPA-4; LPA receptor 4; P2Y purinoceptor 9; P2Y5-like receptor; purinergic receptor 9; G protein-coupled receptor 23; G-protein coupled receptor 23

UniProt Comments for LPAR4

LPAR4: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1- alkyl- > 1-alkenyl-LPA. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq21.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; lipid binding

Biological Process: G-protein coupled receptor protein signaling pathway

Research Articles on LPAR4

1. Our data suggest that LPA4 signaling potentially modulates malignant behavior of SQ-20B cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LPAR4 antibody

Reference Product	PubMed Publications
LPAR1 antibody	>4 publications with LPAR4 and LPAR1
LPAR2 antibody	>3 publications with LPAR4 and LPAR2
LPAR3 antibody	>2 publications with LPAR4 and LPAR3

Pathways associated with anti-LPAR4 antibody

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies	Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
LPA Receptor Mediated Events Pathway antibodies	LPA Receptor Mediated Events Pathway Diagram
LPA4-mediated Signaling Events Pathway antibodies	LPA4-mediated Signaling Events Pathway Diagram

Diseases associated with anti-LPAR4 antibody

Disease Name	Pubmed Publications
Liver Neoplasms Antibodies	>1 publications with LPAR4 and Liver Neoplasms
Neoplasm Metastasis Antibodies	>1 publications with LPAR4 and Neoplasm Metastasis
Liver Diseases Antibodies	>1 publications with LPAR4 and Liver Diseases
Skin Neoplasms Antibodies	>1 publications with LPAR4 and Skin Neoplasms
Disease Models, Animal Antibodies	>1 publications with LPAR4 and Disease Models, Animal
Liver Neoplasms, Experimental Antibodies	>1 publications with LPAR4 and Liver Neoplasms, Experimental
Inflammation Antibodies	>1 publications with LPAR4 and Inflammation
Neoplasms, Experimental Antibodies	>1 publications with LPAR4 and Neoplasms, Experimental
Necrosis Antibodies	>1 publications with LPAR4 and Necrosis

Organs/Tissues associated with anti-LPAR4 antibody

Organ/Tissue Name	Pubmed Publications
Embryonic Tissue Antibodies	>3 publications with LPAR4 and Embryonic Tissue
Thymus Antibodies	>1 publications with LPAR4 and Thymus
Eye Antibodies	>1 publications with LPAR4 and Eye
Brain Antibodies	>1 publications with LPAR4 and Brain