Rabbit Anti-LRRC4 Polyclonal Antibody – Cat# MBS6317138

LRRC4 Antibody – Rabbit Polyclonal

Name: LRRC4 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6317138
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6317138

MaxLight550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor546, 555, DyLight549, Cy3, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction… More details

$1060 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LRRC4, Polyclonal Antibody

Full Product Name

LRRC4, CT (LRRC4, BAG, Leucine-rich repeat-containing protein 4, Brain tumor-associated protein BAG, Nasopharyngeal carcinoma-associated gene 14 protein, Netrin-G2 ligand) (MaxLight 550)

Product Gene Name

anti-LRRC4 antibody

Product Synonym Names

LRRC4; BAG; Leucine-rich repeat-containing protein 4; Brain tumor-associated protein BAG; Nasopharyngeal carcinoma-associated gene 14 protein; Netrin-G2 ligand

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

72,717 Da

Chromosome Location

Chromosome: 7; NC_000007.13 (127667124..127671002, complement). Location: 7q31.3

OMIM

610486

3D Structure

ModBase 3D Structure for Q9HBW1

Immunogen

LRRC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 536~565 amino acids from the C-terminal region of human LRRC4.

Conjugate

MaxLight550

Note

Preservative Free

Product Categories/Family for anti-LRRC4 antibody

Antibodies; Netrin

Applications Tested/Suitable for anti-LRRC4 antibody

Immunohistochemistry (IHC), FLISA, Western Blot (WB)

Application Notes for anti-LRRC4 antibody

IHC: 1:50-100
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.

Product References and Citations for anti-LRRC4 antibody

Wu, M., et al. J. Cell. Physiol. 214(1):65-74(2008). Zhang, Z., et al. BMC Mol. Biol. 9, 99 (2008): Wu, M., et al. J. Neurooncol. 80(2):133-142(2006). Wu, M., et al. Mol. Biol. Cell 17(8):3534-3542(2006). Zhang, Q.H., et al. Acta Biochim. Biophys. Sin. (Shanghai) 37(10):680-687(2005). Zhang, Q.H., et al. Acta Biochim. Biophys. Sin. (Shanghai) 37(8):532-540(2005).

Other Notes

Small volumes of anti-LRRC4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LRRC4 purchase

MBS6317138 is an antibody targeting LRRC4. Also known as LRRC4, CT (LRRC4, BAG, Leucine-rich repeat-containing protein 4, Brain tumor-associated protein BAG, Nasopharyngeal carcinoma-associated gene 14 protein, Netrin-G2 ligand) (MaxLight 550). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LRRC4. It may not necessarily be applicable to this product.

NCBI GI #

15029530

NCBI GeneID

64101

NCBI Accession #

NP_071426.1

UniProt Primary Accession #

Q9HBW1

UniProt Secondary Accession #

Q14DU9; Q6ZMI8; Q96A85; A4D0Y9

UniProt Related Accession #

Q9HBW1

GenBank Nucleotide #

NM_022143.4

NCBI Official Full Name

leucine-rich repeat-containing protein 4

NCBI Official Synonym Full Names

leucine rich repeat containing 4

NCBI Official Symbol

LRRC4

NCBI Official Synonym Symbols

NAG14; NGL-2

UniProt Protein Name

Leucine-rich repeat-containing protein 4

UniProt Synonym Protein Names

Brain tumor-associated protein BAG; Nasopharyngeal carcinoma-associated gene 14 protein; Netrin-G2 ligand

Protein Family

Leucine-rich repeat-containing protein

UniProt Gene Name

LRRC4

UniProt Synonym Gene Names

BAG; NGL-2

UniProt Entry Name

LRRC4_HUMAN

NCBI Protein Information

leucine-rich repeat-containing protein 4; netrin-G2 ligand; leucine-rich repeat-containing 4; brain tumor-associated protein BAG; brain tumor associated protein LRRC4; nasopharyngeal carcinoma-associated gene 14 protein

NCBI Summary for LRRC4

This gene is significantly downregulated in primary brain tumors. The exact function of the protein encoded by this gene is unknown. [provided by RefSeq, Jul 2008]

UniProt Comments for LRRC4

LRRC4: Synaptic adhesion protein. Regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. Organize the lamina/pathway-specific differentiation of dendrites. Plays a important role for auditory synaptic responses. Involved in the suppression of glioma.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 7q31.3

Cellular Component: postsynaptic membrane; dendritic spine; integral to membrane; excitatory synapse; cell junction

Molecular Function: protein binding

Biological Process: synapse organization and biogenesis; regulation of synapse organization and biogenesis

Research Articles on LRRC4

1. LRRC4 inhibited the miR-185 pathway function in glioma

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LRRC4 antibody

Reference Product	PubMed Publications
CDK2 antibody	>1 publications with LRRC4 and CDK2
PCNA antibody	>1 publications with LRRC4 and PCNA

Pathways associated with anti-LRRC4 antibody

Products by Pathway	Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram

Diseases associated with anti-LRRC4 antibody

Disease Name	Pubmed Publications
Schizophrenia Antibodies	>1 publications with LRRC4 and Schizophrenia

Organs/Tissues associated with anti-LRRC4 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>14 publications with LRRC4 and Brain
Embryonic Tissue Antibodies	>2 publications with LRRC4 and Embryonic Tissue
Kidney Antibodies	>1 publications with LRRC4 and Kidney
Vascular Antibodies	>1 publications with LRRC4 and Vascular
Blood Antibodies	>1 publications with LRRC4 and Blood