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LRRF2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6317318

LRRF2 may function as activator of the canonical Wnt signaling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin. More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LRRF2, Polyclonal Antibody
Full Product Name
LRRF2, CT (Leucine-rich repeat flightless-interacting protein 2, LRR FLII-interacting protein 2,LRRFIP2) (AP)
Product Gene Name
Product Synonym Gene Name
LRRFIP2
Product Synonym Names
Leucine-rich repeat flightless-interacting protein 2; LRR FLII-interacting protein 2,LRRFIP2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
OMIM
614043
3D Structure
ModBase 3D Structure for Q9Y608
Immunogen
LRRF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human LRRF2.
Conjugate
AP
Note
Preservative Free
Applications Tested/Suitable for anti-LRRF2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-LRRF2 antibody
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-LRRF2 antibody

Dai, P., et al. J. Immunol. 182(6):3450-3460(2009). Olsen, J.V., et al. Cell 127(3):635-648(2006). Liu, J., et al. Proc. Natl. Acad. Sci. U.S.A. 102(6):1927-1932(2005).

Other Notes

Small volumes of anti-LRRF2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LRRF2 purchase

MBS6317318 is an antibody targeting LRRF2. Also known as LRRF2, CT (Leucine-rich repeat flightless-interacting protein 2, LRR FLII-interacting protein 2,LRRFIP2) (AP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LRRF2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
leucine-rich repeat flightless-interacting protein 2 isoform 1
NCBI Official Synonym Full Names
leucine rich repeat (in FLII) interacting protein 2
NCBI Official Symbol
LRRFIP2
NCBI Official Synonym Symbols
HUFI-2
UniProt Protein Name
Leucine-rich repeat flightless-interacting protein 2
UniProt Gene Name
LRRFIP2
UniProt Synonym Gene Names
LRR FLII-interacting protein 2
UniProt Entry Name
LRRF2_HUMAN
NCBI Protein Information
leucine-rich repeat flightless-interacting protein 2; LRR FLII-interacting protein 2

UniProt Comments for LRRF2

LRRFIP2: May function as activator of the canonical Wnt signaling pathway, in association with DVL3, upstream of CTNNB1/beta- catenin. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. Belongs to the LRRFIP family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 3p22.2

Molecular Function: protein binding; LRR domain binding

Biological Process: Wnt receptor signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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