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ZIC4 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS631818

This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. This gene is closely linked to… More details

$880 / 0.1 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
ZIC4, Monoclonal Antibody
Full Product Name
ZIC4 (Zic Family Member 4, Zinc Family Member 4 Protein HZIC4, Zinc Finger Protein Of The Cerebellum 4, Zinc Finger Protein ZIC 4) (Azide Free)
Product Gene Name
Product Synonym Names
Anti -ZIC4 (Zic Family Member 4, Zinc Family Member 4 Protein HZIC4, Zinc Finger Protein Of The Cerebellum 4, Zinc Finger Protein ZIC 4) (Azide Free)
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
11C968
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human ZIC4.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
20,817 Da
Chromosome Location
Chromosome: 3; NC_000003.11 (147103835..147124407, complement). Location: 3q24
3D Structure
ModBase 3D Structure for Q6ZTI2
Immunogen
Recombinant human protein corresponding to aa249-320 of ZIC4.
Applications Tested/Suitable for anti-ZIC4 antibody
ELISA (EL/EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-ZIC4 antibody
Suitable for use in ELISA, Immunofluorescence, and Western Blot.
Dilution: ELISA: 1ug/ml-3ng/ml
Western Blot: 1:500-1:1,000

Other Notes

Small volumes of anti-ZIC4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZIC4 purchase

MBS631818 is an antibody targeting ZIC4. Also known as ZIC4 (Zic Family Member 4, Zinc Family Member 4 Protein HZIC4, Zinc Finger Protein Of The Cerebellum 4, Zinc Finger Protein ZIC 4) (Azide Free). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ZIC4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
zinc finger protein ZIC 4 isoform 2
NCBI Official Synonym Full Names
Zic family member 4
NCBI Official Symbol
ZIC4
NCBI Official Synonym Symbols
FLJ42609; FLJ45833
UniProt Protein Name
cDNA FLJ44632 fis, clone BRACE2019348, moderately similar to Zinc finger protein ZIC4
Protein Family
UniProt Entry Name
Q6ZTI2_HUMAN
NCBI Protein Information
zinc finger protein ZIC 4; OTTHUMP00000215404; OTTHUMP00000215406; OTTHUMP00000215407; OTTHUMP00000215408; zinc family member 4 protein HZIC4; zinc finger protein of the cerebellum 4

NCBI Summary for ZIC4

This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 1, a related family member on chromosome 3. Heterozygous deletion of these linked genes is involved in Dandy-Walker malformation, which is a congenital cerebellar malformation. Multiple transcript variants have been identified for this gene. [provided by RefSeq]
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UniProt Comments for ZIC4

ZIC4: Binds to DNA. Belongs to the GLI C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 3q24

Cellular Component: nucleus

Molecular Function: DNA binding; metal ion binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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