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TRIM35 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS631972

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified.… More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TRIM35, Monoclonal Antibody
Full Product Name
TRIM35 (Tripartite Motif Containing 35, Tripartite Motif-containing 35, KIAA1098, Hemopoietic lineage switch protein 5, HLS5) (Azide Free)
Product Gene Name
Product Synonym Names
Anti -TRIM35 (Tripartite Motif Containing 35, Tripartite Motif-containing 35, KIAA1098, Hemopoietic lineage switch protein 5, HLS5) (Azide Free)
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
11C907
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human TRIM35.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
56,540 Da
Chromosome Location
Chromosome: 8; NC_000008.10 (27142404..27168834, complement). Location: 8p21.2
3D Structure
ModBase 3D Structure for Q9UPQ4
Immunogen
Recombinant protein corresponding to aa394-494 of human TRIM35.
Applications Tested/Suitable for anti-TRIM35 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-TRIM35 antibody
Suitable for use in ELISA, Immunohistochemistry, and Western Blot.
Dilution: ELISA: 1ug/ml-3ng/ml
Western Blot: 1:500-1:1,000
Immunohistochemistry (paraffin): 1.5ug/ml

Other Notes

Small volumes of anti-TRIM35 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRIM35 purchase

MBS631972 is an antibody targeting TRIM35. Also known as TRIM35 (Tripartite Motif Containing 35, Tripartite Motif-containing 35, KIAA1098, Hemopoietic lineage switch protein 5, HLS5) (Azide Free). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for TRIM35. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tripartite motif-containing protein 35 isoform 2
NCBI Official Synonym Full Names
tripartite motif containing 35
NCBI Official Symbol
TRIM35
NCBI Official Synonym Symbols
HLS5; MAIR; KIAA1098; MGC17233
UniProt Protein Name
Tripartite motif-containing protein 35
UniProt Synonym Protein Names
Hemopoietic lineage switch protein 5
UniProt Gene Name
TRIM35
UniProt Synonym Gene Names
HLS5; KIAA1098
UniProt Entry Name
TRI35_HUMAN
NCBI Protein Information
tripartite motif-containing protein 35; OTTHUMP00000128221; OTTHUMP00000225153; tripartite motif-containing 35; hemopoietic lineage switch protein 5

UniProt Comments for TRIM35

TRIM35: May play a role as a tumor suppressor. Implicated in the cell death mechanism. Belongs to the TRIM/RBCC family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 8p21.2

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: zinc ion binding

Biological Process: negative regulation of cell proliferation; apoptosis; positive regulation of apoptosis; innate immune response; negative regulation of mitotic cell cycle
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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