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MMP11 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6321324

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
MMP11, Polyclonal Antibody
Full Product Name
MMP11, CT (MMP11, STMY3, Stromelysin-3, Matrix metalloproteinase-11) (MaxLight 550)
Product Gene Name
Product Synonym Names
MMP11; STMY3; Stromelysin-3; Matrix metalloproteinase-11
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
54,590 Da
Chromosome Location
Chromosome: 22; NC_000022.10 (24115036..24126503). Location: 22q11.23
OMIM
185261
3D Structure
ModBase 3D Structure for P24347
Immunogen
MMP11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 398-428 amino acids from the C-terminal region of human MMP11.
Conjugate
MaxLight550
Note
Preservative Free
Applications Tested/Suitable for anti-MMP11 antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes for anti-MMP11 antibody
IHC: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.

Product References and Citations for anti-MMP11 antibody

Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010): Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Nalpas, B., et al. Gut 59(8):1120-1126(2010). Ban, J.Y., et al. Life Sci. 86 (19-20), 756-759 (2010): Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010).

Other Notes

Small volumes of anti-MMP11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MMP11 purchase

MBS6321324 is an antibody targeting MMP11. Also known as MMP11, CT (MMP11, STMY3, Stromelysin-3, Matrix metalloproteinase-11) (MaxLight 550). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MMP11. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
stromelysin-3 preproprotein
NCBI Official Synonym Full Names
matrix metallopeptidase 11 (stromelysin 3)
NCBI Official Symbol
MMP11
NCBI Official Synonym Symbols
ST3; SL-3; STMY3
UniProt Protein Name
Stromelysin-3
UniProt Synonym Protein Names
Matrix metalloproteinase-11
Protein Family
UniProt Gene Name
MMP11
UniProt Synonym Gene Names
STMY3; SL-3; ST3; MMP-11
UniProt Entry Name
MMP11_HUMAN
NCBI Protein Information
stromelysin-3; MMP-11; stromelysin III

UniProt Comments for MMP11

MMP11: May play an important role in the progression of epithelial malignancies. Belongs to the peptidase M10A family.

Protein type: Extracellular matrix; EC 3.4.24.-; Secreted, signal peptide; Protease; Secreted

Chromosomal Location of Human Ortholog: 22q11.23

Cellular Component: proteinaceous extracellular matrix; Golgi lumen; extracellular region

Molecular Function: zinc ion binding; metalloendopeptidase activity; calcium ion binding

Biological Process: extracellular matrix disassembly; collagen catabolic process; extracellular matrix organization and biogenesis; collagen fibril organization; multicellular organismal development; proteolysis; negative regulation of fat cell differentiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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