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NCDN Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6324104

This gene encodes a leucine-rich cytoplasmic protein, which is highly similar to a mouse protein that negatively regulates Ca/calmodulin-dependent protein kinase II phosphorylation and may be essential for spatial learning processes. Several alternatively… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
NCDN, Polyclonal Antibody
Full Product Name
NCDN, NT (NCDN, KIAA0607, Neurochondrin) (Azide free) (HRP)
Product Gene Name
Product Synonym Names
NCDN; KIAA0607; Neurochondrin
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
78,864 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (36023393..36032380). Location: 1p34.3
OMIM
AB018739 mRNA
3D Structure
ModBase 3D Structure for Q9UBB6
Immunogen
NCDN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-144 amino acids from the N-terminal region of human NCDN.
Conjugate
HRP
Note
Preservative Free

Product Categories/Family for anti-NCDN antibody

Applications Tested/Suitable for anti-NCDN antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-NCDN antibody
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-NCDN antibody

NCDN Antibody (N-term) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the NCDN antibody detected the NCDN protein (arrow).
Rabbit Anti-NCDN Polyclonal Antibody – Cat# MBS6324104

Product References and Citations for anti-NCDN antibody

Dateki, M., et al. J. Biol. Chem. 280(21):20503-20508(2005). Mochizuki, R., et al. Biochem. Biophys. Res. Commun. 310(4):1219-1226(2003). Tchernev, V.T., et al. Mol. Med. 8(1):56-64(2002). Ohoka, Y., et al. Biochem. Biophys. Res. Commun. 280(1):237-243(2001). Mochizuki, R., et al. Biochim. Biophys. Acta 1490(3):367-368(2000).

Other Notes

Small volumes of anti-NCDN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NCDN purchase

MBS6324104 is an antibody targeting NCDN. Also known as NCDN, NT (NCDN, KIAA0607, Neurochondrin) (Azide free) (HRP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NCDN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
neurochondrin isoform 2
NCBI Official Synonym Full Names
neurochondrin
NCBI Official Symbol
NCDN
UniProt Protein Name
Neurochondrin
Protein Family
UniProt Gene Name
NCDN
UniProt Synonym Gene Names
KIAA0607
NCBI Protein Information
neurochondrin

UniProt Comments for NCDN

Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling (). Required for the spatial learning process. Acts as a negative regulator of Ca2+-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin-concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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