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WRB Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS632631

This gene encodes a basic nuclear protein of unknown function. The gene is widely expressed in adult and fetal tissues. Since the region proposed to contain the gene(s) for congenital heart disease (CHD) in Down syndrome (DS) patients has been restricted to… More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
WRB, Monoclonal Antibody
Full Product Name
WRB (Tryptophan-rich Protein, Congenital Heart Disease 5 Protein, CHD5, WRB Tryptophan Rich Basic Protein) (Azide Free)
Product Gene Name
Product Synonym Names
Anti -WRB (Tryptophan-rich Protein, Congenital Heart Disease 5 Protein, CHD5, WRB Tryptophan Rich Basic Protein) (Azide Free)
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
11C959
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human WRB.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
19,233 Da
Chromosome Location
Chromosome: 21; NC_000021.8 (40752213..40769815). Location: 21q22.3
3D Structure
ModBase 3D Structure for Q0VGA7
Immunogen
Recombinant protein corresponding to aa29-102 of human WRB.
Applications Tested/Suitable for anti-WRB antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-WRB antibody
Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1:500-1:1,000
ELISA: 1ug/ml-3ng/ml

Other Notes

Small volumes of anti-WRB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WRB purchase

MBS632631 is an antibody targeting WRB. Also known as WRB (Tryptophan-rich Protein, Congenital Heart Disease 5 Protein, CHD5, WRB Tryptophan Rich Basic Protein) (Azide Free). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for WRB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
WRB protein
NCBI Official Synonym Full Names
tryptophan rich basic protein
NCBI Official Symbol
WRB
NCBI Official Synonym Symbols
CHD5; FLJ51808
UniProt Protein Name
WRB protein
UniProt Gene Name
WRB
UniProt Entry Name
Q0VGA7_HUMAN
NCBI Protein Information
tryptophan-rich protein; OTTHUMP00000069044; OTTHUMP00000069046; OTTHUMP00000109172; OTTHUMP00000165173; congenital heart disease 5 protein

NCBI Summary for WRB

This gene encodes a basic nuclear protein of unknown function. The gene is widely expressed in adult and fetal tissues. Since the region proposed to contain the gene(s) for congenital heart disease (CHD) in Down syndrome (DS) patients has been restricted to 21q22.2-22.3, this gene, which maps to 21q22.3, has a potential role in the pathogenesis of Down syndrome congenital heart disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
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UniProt Comments for WRB

WRB: Receptor for ASNA1/TRC40-mediated insertion of tail- anchored (TA) proteins into the ER membrane. Belongs to the WRB/GET1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: endoplasmic reticulum membrane; integral to membrane; nucleus
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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