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NXN Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6327377

NXN functions as a redox-dependent negative regulator of the Wnt signaling pathway. May function as a transcriptional regulator. May regulate phosphatase 2A (By similarity). More details

$1060 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NXN, Polyclonal Antibody
Full Product Name
NXN, ID (NXN, NRX, Nucleoredoxin) (MaxLight 550)
Product Gene Name
Product Synonym Names
NXN; NRX; Nucleoredoxin
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
48,392 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (702585..883010, complement). Location: 17p13.3
OMIM
AK022676 mRNA
3D Structure
ModBase 3D Structure for Q6DKJ4
Immunogen
NXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-249 amino acids from the Central region of human NXN.
Conjugate
MaxLight550
Note
Preservative Free

Product Categories/Family for anti-NXN antibody

Applications Tested/Suitable for anti-NXN antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes for anti-NXN antibody
IHC: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.

Product References and Citations for anti-NXN antibody

Ollila, H.M., et al. Mol. Psychiatry 14(4):351-353(2009). Funato, Y., et al. Antioxid. Redox Signal. 9(8):1035-1057(2007). Hirota, K., et al. Biochem. Biophys. Res. Commun. 274(1):177-182(2000). Kurooka, H., et al. Genomics 39(3):331-339(1997).

Other Notes

Small volumes of anti-NXN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NXN purchase

MBS6327377 is an antibody targeting NXN. Also known as NXN, ID (NXN, NRX, Nucleoredoxin) (MaxLight 550). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NXN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
nucleoredoxin isoform 1
NCBI Official Synonym Full Names
nucleoredoxin
NCBI Official Symbol
NXN
NCBI Official Synonym Symbols
NRX; TRG-4; FLJ12614
UniProt Protein Name
Nucleoredoxin
Protein Family
UniProt Gene Name
NXN
UniProt Synonym Gene Names
NRX
NCBI Protein Information
nucleoredoxin; nucleoredoxin 1; OTTHUMP00000115356

UniProt Comments for NXN

Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) ().

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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