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PSD95, Postsynaptic Density Protein 95 (DLG4) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS632936

PSD95 (postsynaptic density 95) represent a class of anchoring proteins which serve to localize various neuronal ion channels to post-synaptic densities. PSD95 and related proteins contain PDZ domains, which interact with NMDA receptors and voltage-gated K+… More details

$1125 / 0.1 mg +1 FREE 8GB USB
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Testing Data View PDF
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Product Overview

Online Datasheet in PDF
Product Name
PSD95, Postsynaptic Density Protein 95 (DLG4), Monoclonal Antibody
Full Product Name
PSD95, Postsynaptic Density Protein 95 (PSD-95, PSD95, Post-synaptic Density Protein 95, Synapse-associated Protein 90, SAP90, SAP-90)
Product Gene Name
Product Synonym Names
Anti -PSD95, Postsynaptic Density Protein 95 (PSD-95, PSD95, Post-synaptic Density Protein 95, Synapse-associated Protein 90, SAP90, SAP-90)
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
11C253
Host
Mouse
Species Reactivity
Human, Rat
Form/Format
Supplied as a liquid in 0.1M Tris-Glycine, pH 7.4, 150 mM sodium chloride, 0.05% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes rat PSD95. Species sequence homology: mouse and human.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
31,914 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (7093209..7123369, complement). Location: 17p13.1
3D Structure
ModBase 3D Structure for O14909
Immunogen
Recombinant protein corresponding to human PSD95.
Positive Control
Rat brain tissue lysate

Product Categories/Family for anti-DLG4 antibody

Applications Tested/Suitable for anti-DLG4 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
Application Notes for anti-DLG4 antibody
Suitable for use in Immunohistochemistry, Western Blot and Immunocytochemistry.
Dilution: Western Blot: 0.5ug/ml detects PSD95 on 10ug of rat brain tissue lysate. Rat brain lysate was probed with N5380-25. Proteins were visualized using an IgG (HRP) goat anti-mouse and a chemiluminescence detection system.
Immunohistochemistry: 1:500 detects PSD95 in rat cortex tissue.

Immunohistochemistry (IHC) of anti-DLG4 antibody

Representative lot data. |Paraffin-embedded rat cortex tissue was prepared using heat-induced epitope retrieval in citrate buffer, pH 6.0. Immunostaining was performed using a 1:500 dilution of MBS632936. Staining is seen in the neuronal cellular processes and the cytoplasm.
Mouse Anti-DLG4 Monoclonal Antibody – Cat# MBS632936

Testing Data of anti-DLG4 antibody

Representative lot data. |Rat brain tissue lysate was probed with MBS632936 (0.5ug/ml). |Proteins were visualized using an IgG (HRP) Goat Anti-Mouse and a chemiluminescence detection system. |Arrow indicates PSD95 (~95kD).
Mouse Anti-DLG4 Monoclonal Antibody, Testing Data – Cat# MBS632936

Other Notes

Small volumes of anti-DLG4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DLG4 purchase

MBS632936 is an antibody targeting DLG4. Also known as PSD95, Postsynaptic Density Protein 95 (PSD-95, PSD95, Post-synaptic Density Protein 95, Synapse-associated Protein 90, SAP90, SAP-90). Reactive in Human, Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for DLG4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
post-synaptic density protein 95
NCBI Official Synonym Full Names
discs, large homolog 4 (Drosophila)
NCBI Official Symbol
DLG4
NCBI Official Synonym Symbols
PSD95; SAP90; SAP-90; FLJ97752; FLJ98574
UniProt Protein Name
Discs, large homolog 4 (Drosophila), isoform CRA_d
Protein Family
UniProt Gene Name
DLG4
UniProt Entry Name
O14909_HUMAN
NCBI Protein Information
disks large homolog 4; OTTHUMP00000166066; OTTHUMP00000166067; OTTHUMP00000166068; discs large homolog 4; Tax interaction protein 15; synapse-associated protein 90; postsynaptic density protein 95; post-synaptic density protein 95

NCBI Summary for DLG4

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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