Rabbit Anti-OSTA Polyclonal Antibody – Cat# MBS6329757

Western blot analysis in 293 cell line lysates (35ug/lane) using 039522. OST alpha (arrow) was detected using the purified Pab.

OST Alpha (OSTA) Antibody – Rabbit Polyclonal

Name: OSTA Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6329757
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6329757

MBS6329757 is an antibody targeting OSTA. Also known as OST alpha, CT (OSTA, Organic solute transporter subunit alpha) (AP). Reactive in Human. Host: Rabbit. More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

OST alpha (OSTA), Polyclonal Antibody

Full Product Name

OST alpha, CT (OSTA, Organic solute transporter subunit alpha) (AP)

Product Gene Name

anti-OSTA antibody

Product Synonym Gene Name

OSTalpha

Product Synonym Names

OSTA; Organic solute transporter subunit alpha

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

Purity/Purification

Purified by Protein A and Peptide Affinity Chromatography.

Specificity

Recognizes human OST alpha.

Preparation and Storage

Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

38 kDa (MW of target protein)

OMIM

612084

3D Structure

ModBase 3D Structure for Q86UW1

Immunogen

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 298-327 in the C-terminal region of human OST alpha, UniProt Accession #Q86UW1.

Conjugate

Note

Preservative Free

Product Categories/Family for anti-OSTA antibody

Antibodies; Transport Proteins

Applications Tested/Suitable for anti-OSTA antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-OSTA antibody

Applications are based on unconjugated antibody.

Product References and Citations for anti-OSTA antibody

1. Renner, O., et al. J. Lipid Res. 49(9):2045-2054(2008). 2. Soroka, C.J., et al. BMC Cell Biol. 9, 57 (2008). 3. Sun, A.Q., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 292 (6), G1586-G1593 (2007). 4. Boyer, J.L., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 290 (6), G1124-G1130 (2006). 5. Lim, J., et al. Cell 125(4):801-814(2006).

Other Notes

Small volumes of anti-OSTA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for OSTA. It may not necessarily be applicable to this product.

NCBI GI #

217035113

NCBI GeneID

200931

NCBI Accession #

NP_689885.4

UniProt Primary Accession #

Q86UW1

UniProt Secondary Accession #

Q6ZMC7

UniProt Related Accession #

Q86UW1

GenBank Nucleotide #

NM_152672.5

NCBI Official Full Name

organic solute transporter subunit alpha

NCBI Official Synonym Full Names

solute carrier family 51, alpha subunit

NCBI Official Symbol

SLC51A

NCBI Official Synonym Symbols

OSTA; OSTalpha

UniProt Protein Name

Organic solute transporter subunit alpha

UniProt Synonym Protein Names

Solute carrier family 51 subunit alpha

Protein Family

Organic solute transporter

UniProt Gene Name

SLC51A

UniProt Synonym Gene Names

OSTA; OST-alpha

UniProt Entry Name

OSTA_HUMAN

NCBI Protein Information

organic solute transporter subunit alpha

UniProt Comments for OSTA

OSTalpha: Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. Efficiently transports the major species of bile acids. Belongs to the OST-alpha family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q29

Cellular Component: endoplasmic reticulum membrane; integral to membrane; plasma membrane; protein complex

Molecular Function: protein heterodimerization activity; protein homodimerization activity; transporter activity

Biological Process: bile acid and bile salt transport; transport

Research Articles on OSTA

1. Ostbeta is required for both proper trafficking of Ostalpha and formation of the functional transport unit, and identify specific residues of Ostbeta critical for these processes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-OSTA antibody

Reference Product	PubMed Publications
SLC10A1 antibody	>1 publications with OSTA and SLC10A1
SLC10A2 antibody	>1 publications with OSTA and SLC10A2
SLC51B antibody	>1 publications with OSTA and SLC51B

Pathways associated with anti-OSTA antibody

Products by Pathway	Pathway Diagram
Bile Secretion Pathway antibodies	Bile Secretion Pathway Diagram
Bile Secretion Pathway antibodies	Bile Secretion Pathway Diagram
Drug Induction Of Bile Acid Pathway antibodies	Drug Induction Of Bile Acid Pathway Diagram

Diseases associated with anti-OSTA antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>1 publications with OSTA and Inflammation

Organs/Tissues associated with anti-OSTA antibody

Organ/Tissue Name	Pubmed Publications
Intestine Antibodies	>2 publications with OSTA and Intestine