Rabbit Anti-P2RX6 Polyclonal Antibody – Cat# MBS6330234

P2RX6 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the P2RX6 antibody detected the P2RX6 protein (arrow).

P2RX6 Antibody – Rabbit Polyclonal

Name: P2RX6 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6330234
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6330234

The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

P2RX6, Polyclonal Antibody

Full Product Name

P2RX6, ID (P2RX6, P2RXL1, P2X6, P2X purinoceptor 6, ATP receptor, P2XM, Purinergic receptor, Purinergic receptor P2X-like 1) (Azide free) (HRP)

Product Gene Name

anti-P2RX6 antibody

Product Synonym Names

P2RX6; P2RXL1; P2X6; P2X purinoceptor 6; ATP receptor; P2XM; Purinergic receptor; Purinergic receptor P2X-like 1

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

45,808 Da

OMIM

608077

3D Structure

ModBase 3D Structure for O15547

Immunogen

P2RX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of human P2RX6.

Conjugate

HRP

Note

Preservative Free

Product Categories/Family for anti-P2RX6 antibody

Antibodies; Receptors

Applications Tested/Suitable for anti-P2RX6 antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-P2RX6 antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-P2RX6 antibody

Trynka, G., et al. Gut 58(8):1078-1083(2009). Luke, M.M., et al. Stroke 40(2):363-368(2009). Palomino-Doza, J., et al. Hypertension 52(5):980-985(2008). Shiffman, D., et al. Arterioscler. Thromb. Vasc. Biol. 28(1):173-179(2008). Dubyak, G.R. Mol. Pharmacol. 72(6):1402-1405(2007).

Other Notes

Small volumes of anti-P2RX6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for P2RX6 purchase

MBS6330234 is an antibody targeting P2RX6. Also known as P2RX6, ID (P2RX6, P2RXL1, P2X6, P2X purinoceptor 6, ATP receptor, P2XM, Purinergic receptor, Purinergic receptor P2X-like 1) (Azide free) (HRP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for P2RX6. It may not necessarily be applicable to this product.

NCBI GI #

227116341

NCBI GeneID

9127

NCBI Accession #

NP_001153026.1

NCBI Related Accession #

NP_005437.2

UniProt Primary Accession #

O15547

UniProt Secondary Accession #

Q32MB6; Q58F04; Q6IC33; Q9UL50; F6V3D7

UniProt Related Accession #

O15547

GenBank Nucleotide #

NM_001159554.1

NCBI Official Full Name

P2X purinoceptor 6 isoform 2

NCBI Official Synonym Full Names

purinergic receptor P2X 6

NCBI Official Symbol

P2RX6

NCBI Official Synonym Symbols

P2X6; P2XM; P2RXL1

UniProt Protein Name

P2X purinoceptor 6

UniProt Synonym Protein Names

ATP receptor; P2XM; Purinergic receptor; Purinergic receptor P2X-like 1

Protein Family

P2X purinoceptor

UniProt Gene Name

P2RX6

UniProt Synonym Gene Names

P2RXL1; P2X6; P2X6

UniProt Entry Name

P2RX6_HUMAN

NCBI Protein Information

P2X purinoceptor 6

UniProt Comments for P2RX6

P2X6: Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Channel, cation; Receptor, misc.; Channel, ligand-gated

Chromosomal Location of Human Ortholog: 22q11.21

Cellular Component: cell soma; integral to plasma membrane; postsynaptic density; cytoplasm; dendritic spine; integral to nuclear inner membrane; cell junction

Molecular Function: identical protein binding; transmembrane receptor activity; channel activity; purinergic nucleotide receptor activity; ATP binding; ATP-gated cation channel activity

Biological Process: muscle contraction; transport; protein heterooligomerization; signal transduction; transmembrane transport; protein homooligomerization; cation transport

Research Articles on P2RX6

1. one subunit of P2X2 and two subunits of P2X3 form P2X2/3 heteromeric receptors, whereas two subunits of P2X2 and one subunit of P2X6 constitute P2X2/6 receptors

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-P2RX6 antibody

Products by Pathway	Pathway Diagram
Calcium Signaling Pathway antibodies	Calcium Signaling Pathway Diagram
Calcium Signaling Pathway antibodies	Calcium Signaling Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram