Rabbit Anti-PDZD3 Polyclonal Antibody – Cat# MBS6332570

PDZD3 Antibody – Rabbit Polyclonal

Name: PDZD3 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6332570
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6332570

Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to… More details

$1060 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PDZD3, Polyclonal Antibody

Full Product Name

PDZD3, ID (PDZD3, IKEPP, NHERF4, PDZK2, Na(+)/H(+) exchange regulatory cofactor NHE-RF4, Intestinal and kidney-enriched PDZ protein, Natrium-phosphate cotransporter IIa C-terminal-associated protein 2, PDZ domain-containing protein 2, PDZ domain-containin

Product Gene Name

anti-PDZD3 antibody

Product Synonym Names

PDZD3; IKEPP; NHERF4; PDZK2; Na(+)/H(+) exchange regulatory cofactor NHE-RF4; Intestinal and kidney-enriched PDZ protein; Natrium-phosphate cotransporter IIa C-terminal-associated protein 2; PDZ domain-containing protein 2; PDZ domain-containing protein 3; Sodium-hydrogen exchanger regulatory factor 4

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

61,032 Da

OMIM

607146

3D Structure

ModBase 3D Structure for Q86UT5

Immunogen

PDZD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-285 amino acids from the Central region of human PDZD3.

Conjugate

MaxLight650

Note

Preservative Free

Product Categories/Family for anti-PDZD3 antibody

Antibodies; PDZ Domain

Applications Tested/Suitable for anti-PDZD3 antibody

Western Blot (WB), FLISA

Application Notes for anti-PDZD3 antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-PDZD3 antibody

Zachos, N.C., et al. Cell. Physiol. Biochem. 22 (5-6), 693-704 (2008): Kato, Y., et al. Mol. Pharmacol. 67(3):734-743(2005). Hegedus, T., et al. Biochem. Biophys. Res. Commun. 302(3):454-461(2003). Scott, R.O., et al. J. Biol. Chem. 277(25):22934-22941(2002).

Other Notes

Small volumes of anti-PDZD3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PDZD3 purchase

MBS6332570 is an antibody targeting PDZD3. Also known as PDZD3, ID (PDZD3, IKEPP, NHERF4, PDZK2, Na(+)/H(+) exchange regulatory cofactor NHE-RF4, Intestinal and kidney-enriched PDZ protein, Natrium-phosphate cotransporter IIa C-terminal-associated protein 2, PDZ domain-containing protein 2, PDZ domain-containin. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PDZD3. It may not necessarily be applicable to this product.

NCBI GI #

270483764

NCBI GeneID

79849

NCBI Accession #

NP_001161940.1

NCBI Related Accession #

NP_079067.3

UniProt Primary Accession #

Q86UT5

UniProt Secondary Accession #

Q8N6R4; Q8NAW7; Q8NEX7; Q9H5Z3

UniProt Related Accession #

Q86UT5

GenBank Nucleotide #

NM_001168468.1

NCBI Official Full Name

Na(+)/H(+) exchange regulatory cofactor NHE-RF4 isoform 1

NCBI Official Synonym Full Names

PDZ domain containing 3

NCBI Official Symbol

PDZD3

NCBI Official Synonym Symbols

IKEPP; PDZK2; NHERF4

UniProt Protein Name

Na(+)/H(+) exchange regulatory cofactor NHE-RF4

UniProt Synonym Protein Names

Intestinal and kidney-enriched PDZ protein; Natrium-phosphate cotransporter IIa C-terminal-associated protein 2; Na/Pi cotransporter C-terminal-associated protein 2; NaPi-Cap2; PDZ domain-containing protein 2; PDZ domain-containing protein 3; Sodium-hydrogen exchanger regulatory factor 4

Protein Family

Na(+)/H(+) exchange regulatory cofactor

UniProt Gene Name

PDZD3

UniProt Synonym Gene Names

IKEPP; NHERF4; PDZK2; NHERF-4; Na/Pi cotransporter C-terminal-associated protein 2; NaPi-Cap2

UniProt Entry Name

NHRF4_HUMAN

NCBI Protein Information

Na(+)/H(+) exchange regulatory cofactor NHE-RF4; Na(+)/H(+) exchange regulatory cofactor NHE-RF4; NHERF-4; naPi-Cap2; PDZ domain containing 2; PDZ domain-containing protein 2; PDZ domain-containing protein 3; intestinal and kidney enriched PDZ protein; in

Research Articles on PDZD3

1. The NHERF4 is a novel modulator of luminal fluidity in the intestine by adjusting SLC26A3 expression and activity through a phosphorylation-dependent mechanism.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-PDZD3 antibody

Organ/Tissue Name	Pubmed Publications
Intestine Antibodies	>1 publications with PDZD3 and Intestine