Rabbit Anti-PIGV Polyclonal Antibody – Cat# MBS6333922

PIGV Antibody – Rabbit Polyclonal

Name: PIGV Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6333922
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6333922

Glycosylphosphatidylinositol (GPI) is a complex glycolipid that anchors many proteins to the cell surface. The biosynthetic pathway of GPI is mediated by sequential addition of sugars and other components to phosphatidylinositol. PIGV adds the second mannose… More details

$1060 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PIGV, Polyclonal Antibody

Full Product Name

PIGV, CT (PIGV, GPI mannosyltransferase 2, GPI mannosyltransferase II, Phosphatidylinositol-glycan biosynthesis class V protein) (MaxLight 550)

Product Gene Name

anti-PIGV antibody

Product Synonym Names

PIGV; GPI mannosyltransferase 2; GPI mannosyltransferase II; Phosphatidylinositol-glycan biosynthesis class V protein

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

OMIM

610274

3D Structure

ModBase 3D Structure for Q9NUD9

Immunogen

PIGV antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 342-371 amino acids from the C-terminal region of human PIGV.

Conjugate

MaxLight550

Note

Preservative Free

Product Categories/Family for anti-PIGV antibody

Antibodies; Enzymes; Transferase

Applications Tested/Suitable for anti-PIGV antibody

Western Blot (WB), FLISA

Application Notes for anti-PIGV antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-PIGV antibody

Krawitz, P.M., et al. Nat. Genet. 42(10):827-829(2010). Kang, J.Y., et al. J. Biol. Chem. 280(10):9489-9497(2005). Fabre, A.L., et al. FEBS J. 272(5):1160-1168(2005). Kinoshita, T., et al. Curr Opin Chem Biol 4(6):632-638(2000).

Other Notes

Small volumes of anti-PIGV antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PIGV purchase

MBS6333922 is an antibody targeting PIGV. Also known as PIGV, CT (PIGV, GPI mannosyltransferase 2, GPI mannosyltransferase II, Phosphatidylinositol-glycan biosynthesis class V protein) (MaxLight 550). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PIGV. It may not necessarily be applicable to this product.

NCBI GI #

21361771

NCBI GeneID

55650

NCBI Accession #

NP_060307.2

UniProt Primary Accession #

Q9NUD9

UniProt Related Accession #

Q9NUD9

GenBank Nucleotide #

NP_060307.2

NCBI Official Full Name

GPI mannosyltransferase 2 isoform a

NCBI Official Synonym Full Names

phosphatidylinositol glycan anchor biosynthesis class V

NCBI Official Symbol

PIGV

NCBI Official Synonym Symbols

PIG-V; HPMRS1; GPI-MT-II

UniProt Protein Name

GPI mannosyltransferase 2

UniProt Synonym Protein Names

GPI mannosyltransferase II; GPI-MT-II; Phosphatidylinositol-glycan biosynthesis class V protein; PIG-V

Protein Family

GPI mannosyltransferase

UniProt Gene Name

PIGV

UniProt Synonym Gene Names

GPI-MT-II; PIG-V

UniProt Entry Name

PIGV_HUMAN

NCBI Protein Information

GPI mannosyltransferase 2

NCBI Summary for PIGV

This gene encodes a mannosyltransferase enzyme involved in the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is a complex glycolipid that functions as a membrane anchor for many proteins and plays a role in multiple cellular processes including protein sorting and signal transduction. The encoded protein is localized to the endoplasmic reticulum and transfers the second mannose to the GPI backbone. Mutations in this gene are associated with hyperphosphatasia cognitive disability syndrome. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]

Research Articles on PIGV

1. Data indicate that mannosyltransferases PIGV mutations are the major cause of hyperphosphatasia-mental retardation syndrome (HPMRS) which displays a broad clinical variability regarding associated malformations and growth patterns.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.