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RBMY1A1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS633412

This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. Multiple copies of this gene are found in the AZFb azoospermia factor region of chromosome Y and the… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RBMY1A1, Monoclonal Antibody
Full Product Name
RBMY1A1 (RNA-binding Motif Protein, Y Chromosome, Family 1 Member A1/C, RNA-binding Motif Protein 1, RNA-binding Motif Protein 2, Y Chromosome RNA Recognition Motif 1, hRBMY, RBM1, RBM2, YRRM1, RBMY1C)
Product Gene Name
anti-RBMY1A1 antibody
Product Synonym Names
Anti -RBMY1A1 (RNA-binding Motif Protein, Y Chromosome, Family 1 Member A1/C, RNA-binding Motif Protein 1, RNA-binding Motif Protein 2, Y Chromosome RNA Recognition Motif 1, hRBMY, RBM1, RBM2, YRRM1, RBMY1C)
Clonality
Monoclonal
Isotype
IgG2a, k
Clone Number
3G1
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Purified
Purified.
Specificity
Recognizes human RBMY1A1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
55,784 Da
Chromosome Location
Chromosome: Y; NC_000024.9 (23696790..23711212). Location: Yq11.223
OMIM
400006
3D Structure
ModBase 3D Structure for Q15414
Immunogen
RBMY1A1 (NP_001007527, 257-357aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-RBMY1A1 antibody

Antibodies; Abs to Binding Proteins
Applications Tested/Suitable for anti-RBMY1A1 antibody
ELISA (EL/EIA)
Application Notes for anti-RBMY1A1 antibody
Suitable for use in ELISA.

Other Notes

Small volumes of anti-RBMY1A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RBMY1A1 purchase

MBS633412 is an antibody targeting RBMY1A1. Also known as RBMY1A1 (RNA-binding Motif Protein, Y Chromosome, Family 1 Member A1/C, RNA-binding Motif Protein 1, RNA-binding Motif Protein 2, Y Chromosome RNA Recognition Motif 1, hRBMY, RBM1, RBM2, YRRM1, RBMY1C). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for RBMY1A1. It may not necessarily be applicable to this product.

NCBI GI #
4826974
NCBI GeneID
5940
NCBI Accession #
NP_005049.1
UniProt Primary Accession #
Q15414
UniProt Secondary Accession #
Q15376; Q15377; Q6NSB5; Q86VU6; Q8NHR0
UniProt Related Accession #
Q13369; Q15414
GenBank Nucleotide #
NM_005058.2
NCBI Official Full Name
RNA-binding motif protein, Y chromosome, family 1 member A1/C
NCBI Official Synonym Full Names
RNA binding motif protein, Y-linked, family 1, member A1
NCBI Official Symbol
RBMY1A1
NCBI Official Synonym Symbols
RBM; RBM1; RBM2; RBMY; YRRM1; YRRM2; RBMY1C; MGC181956
UniProt Protein Name
RNA-binding motif protein, Y chromosome, family 1 member A1/C
UniProt Synonym Protein Names
RNA-binding motif protein 1; RNA-binding motif protein 2; Y chromosome RNA recognition motif 1
Protein Family
RNA-binding motif protein
UniProt Gene Name
RBMY1A1
UniProt Synonym Gene Names
RBM1; RBM2; YRRM1; YRRM2
UniProt Entry Name
RBY1A_HUMAN
NCBI Protein Information
RNA-binding motif protein, Y chromosome, family 1 member A1/C; hRBMY; OTTHUMP00000040529; RNA binding protein; RNA binding motif protein 2; RNA-binding motif protein 1; RNA-binding motif protein 2; y chromosome RNA recognition motif 1; RNA binding motif protein, Y chromosome, family 1, member A1

UniProt Comments for RBMY1A1

RBMY1A1: RNA-binding protein involved in pre-mRNA splicing. Required for sperm development. Acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN. Binds non-specifically to mRNAs. Interacts with splicing factor proteins SFRS3/SRP20, TRA2B/SFRS10, KHDRBS1/SAM68 and KHDRBS3.

Protein type: RNA splicing

Chromosomal Location of Human Ortholog: Yq11.223

Cellular Component: nucleus

Molecular Function: mRNA binding; protein binding; nucleotide binding

Biological Process: RNA splicing; mRNA processing; regulation of alternative nuclear mRNA splicing, via spliceosome

Disease: Spermatogenic Failure, Y-linked, 2
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Research Articles on RBMY1A1

1. regulates germline-specific splicing events; ectopic expression stimulated the inclusion of a testis-enriched exon

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RBMY1A1 antibody

 Reference Product  PubMed Publications
 TRA2B antibody  >2 publications with RBMY1A1 and TRA2B
 SRSF3 antibody  >1 publications with RBMY1A1 and SRSF3

Organs/Tissues associated with anti-RBMY1A1 antibody

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >32 publications with RBMY1A1 and Testis
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