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PLAA Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6334600

PLAA stimulates human neutrophil aggregation and release of lysosomal enzymes, superoxide, and eicosanoids. It plays an important role in the regulation of specific inflammatory processes connected to such diseases as inflammatory bowel disease, pancreatitis,… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PLAA, Polyclonal Antibody
Full Product Name
PLAA, ID (PLAP, PLA2P) (FITC)
Product Gene Name
Product Synonym Names
PLAP; PLA2P
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
795
OMIM
603873
3D Structure
ModBase 3D Structure for Q9Y263
Immunogen
PLAA antibody is generated from rabbits immunized with a KLH conjugated Synthetic peptide selected from the center region of human PLAA.
Conjugate
FITC
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-PLAA antibody

Applications Tested/Suitable for anti-PLAA antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes for anti-PLAA antibody
IHC: 1:10-50
FLISA: 1:1,000
WB: 1:50-100
Applications are based on unconjugated antibody.

Immunohistochemistry (IHC) of anti-PLAA antibody

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with PLAA antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-PLAA Polyclonal Antibody – Cat# MBS6334600

Product References and Citations for anti-PLAA antibody

Koumanov, K., Cell Biol. Int. 27 (10), 871-877 (2003). Kozlenkov, A., J. Biol. Chem. 277 (25), 22992-22999 (2002). Beatty, B.G., Genomics 62 (3), 529-532 (1999).

Other Notes

Small volumes of anti-PLAA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLAA purchase

MBS6334600 is an antibody targeting PLAA. Also known as PLAA, ID (PLAP, PLA2P) (FITC). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PLAA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Phospholipase A-2-activating protein
NCBI Official Synonym Full Names
phospholipase A2-activating protein
NCBI Official Symbol
PLAA
NCBI Official Synonym Symbols
DOA1; PLAP; PLA2P
UniProt Protein Name
Phospholipase A-2-activating protein
UniProt Gene Name
PLAA
UniProt Synonym Gene Names
PLAP; PLA2P; PLAP
UniProt Entry Name
PLAP_HUMAN
NCBI Protein Information
phospholipase A-2-activating protein; DOA1 homolog; phospholipase A2 activating protein

UniProt Comments for PLAA

PLAA: phospholipase A2 activating protein. A regulator of the production of eicosanoids and prostaglandin E(2) in immune and inflammatory responses. Belongs to the WD repeat PLAP family.

Protein type: Activator

Chromosomal Location of Human Ortholog: 9p21

Molecular Function: phospholipase A2 activator activity; protein binding

Biological Process: positive regulation of catalytic activity; phospholipid metabolic process; signal transduction; inflammatory response
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PLAA antibody

 Reference Product  PubMed Publications
 VCP antibody  >3 publications with PLAA and VCP
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