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CD101 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS633482

CD101 is a 140kD homodimeric cell surface glycoprotein expressed primarily by monocytes, granulocytes, dendritic cells and activated T lymphocytes. Studies suggest that CD101 plays a major role in the activation of T cells by skin dendritic cells. More details

$1135 / 0.2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD101, Monoclonal Antibody
Full Product Name
CD101 (CD101 Molecule, Cell Surface Glycoprotein V7, EWI101, EWI-101, Glu-Trp-Ile EWI Motif-containing Protein 101, Immunoglobulin Superfamily Member 2, IgSF2, V7)
Product Gene Name
Product Synonym Names
Anti -CD101 (CD101 Molecule, Cell Surface Glycoprotein V7, EWI101, EWI-101, Glu-Trp-Ile EWI Motif-containing Protein 101, Immunoglobulin Superfamily Member 2, IgSF2, V7)
Clonality
Monoclonal
Isotype
IgG1
Clone Number
BB27
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH7.4, 0.09% sodium azide.
Purity/Purification
Purified
Purified
Specificity
Recognizes human CD101.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
114,205 Da
3D Structure
ModBase 3D Structure for A8E0Y8
Immunogen
Human thymic clone B12.

Product Categories/Family for anti-Cd101 antibody

Applications Tested/Suitable for anti-Cd101 antibody
Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes for anti-Cd101 antibody
Suitable for use in Flow Cytometry, Immunoprecipitation and Immunohistochemistry.
Dilution: Flow Cytometry: 10ul labels of a 1:50-1:100 working dilution to 10e6 cells in 100ul.
Immunohistochemistry: frozen

Other Notes

Small volumes of anti-Cd101 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cd101 purchase

MBS633482 is an antibody targeting Cd101. Also known as CD101 (CD101 Molecule, Cell Surface Glycoprotein V7, EWI101, EWI-101, Glu-Trp-Ile EWI Motif-containing Protein 101, Immunoglobulin Superfamily Member 2, IgSF2, V7). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for Cd101. It may not necessarily be applicable to this product.

NCBI GI #
UniProt Primary Accession #
UniProt Secondary Accession #
NCBI Official Full Name
CD101 protein
UniProt Protein Name
Immunoglobulin superfamily member 2
UniProt Synonym Protein Names
Glu-Trp-Ile EWI motif-containing protein 101
UniProt Gene Name
Cd101
UniProt Synonym Gene Names
Igsf2
UniProt Entry Name
IGSF2_MOUSE

UniProt Comments for Cd101

IGSF2: Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3- induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells.

Protein type: Immunoglobulin superfamily; Membrane protein, integral

Cellular Component: membrane; integral to membrane

Biological Process: positive regulation of myeloid leukocyte differentiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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