Rabbit Anti-PPFIBP1 Polyclonal Antibody – Cat# MBS6336232

PPFIBP1 Antibody – Rabbit Polyclonal

Name: PPFIBP1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6336232
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6336232

The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon… More details

$1060 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PPFIBP1, Polyclonal Antibody

Full Product Name

PPFIBP1, ID (PPFIBP1, KIAA1230, Liprin-beta-1, Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1, hSGT2) (MaxLight 550)

Product Gene Name

anti-PPFIBP1 antibody

Product Synonym Names

PPFIBP1; KIAA1230; Liprin-beta-1; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1; hSGT2

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

OMIM

603141

3D Structure

ModBase 3D Structure for Q86W92

Immunogen

PPFIBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 587-617 amino acids from the Central region of human PPFIBP1.

Conjugate

MaxLight550

Note

Preservative Free

Product Categories/Family for anti-PPFIBP1 antibody

Antibodies; Enzymes; Phosphatase

Applications Tested/Suitable for anti-PPFIBP1 antibody

Western Blot (WB), FLISA

Application Notes for anti-PPFIBP1 antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-PPFIBP1 antibody

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Norrmen, C., et al. Blood 115(4):906-909(2010). Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007): Olsen, J.V., et al. Cell 127(3):635-648(2006). Jin, J., et al. Curr. Biol. 14(16):1436-1450(2004).

Other Notes

Small volumes of anti-PPFIBP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPFIBP1 purchase

MBS6336232 is an antibody targeting PPFIBP1. Also known as PPFIBP1, ID (PPFIBP1, KIAA1230, Liprin-beta-1, Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1, hSGT2) (MaxLight 550). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PPFIBP1. It may not necessarily be applicable to this product.

NCBI GI #

29294627

NCBI GeneID

8496

NCBI Accession #

NP_003613.2

NCBI Related Accession #

NP_803193.1

UniProt Primary Accession #

Q86W92

UniProt Related Accession #

Q86W92

GenBank Nucleotide #

NP_003613.2

NCBI Official Full Name

liprin-beta-1 isoform 1

NCBI Official Synonym Full Names

PPFIA binding protein 1

NCBI Official Symbol

PPFIBP1

NCBI Official Synonym Symbols

L2; SGT2; hSGT2; hSgt2p

UniProt Protein Name

Liprin-beta-1

UniProt Synonym Protein Names

Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1; PTPRF-interacting protein-binding protein 1; hSGT2

Protein Family

Liprin

UniProt Gene Name

PPFIBP1

UniProt Synonym Gene Names

KIAA1230; PTPRF-interacting protein-binding protein 1

UniProt Entry Name

LIPB1_HUMAN

NCBI Protein Information

liprin-beta-1

UniProt Comments for PPFIBP1

liprin beta 1: a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Five alternatively spliced isoforms have been described.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 12p12.1

Cellular Component: focal adhesion; plasma membrane

Biological Process: cell adhesion

Research Articles on PPFIBP1

1. liprin beta-1 is associated with expression of kank 1 and 2 proteins in melanoma

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.