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PPIL3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6336318

This gene encodes a member of the cyclophilin family. Cyclophilins catalyze the cis-trans isomerization of peptidylprolyl imide bonds in oligopeptides. They have been proposed to act either as catalysts or as molecular chaperones in protein-folding events.… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PPIL3, Polyclonal Antibody
Full Product Name
PPIL3, CT (PPIL3, Peptidyl-prolyl cis-trans isomerase-like 3, Cyclophilin J, Cyclophilin-like protein PPIL3, Rotamase PPIL3) (MaxLight 405)
Product Gene Name
Product Synonym Names
PPIL3; Peptidyl-prolyl cis-trans isomerase-like 3; Cyclophilin J; Cyclophilin-like protein PPIL3; Rotamase PPIL3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
18,627 Da
OMIM
615811
3D Structure
ModBase 3D Structure for Q9H2H8
Immunogen
PPIL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-146 amino acids from the C-terminal region of human PPIL3.
Conjugate
MaxLight405
Note
Preservative Free

Product Categories/Family for anti-PPIL3 antibody

Applications Tested/Suitable for anti-PPIL3 antibody
Western Blot (WB), FLISA
Application Notes for anti-PPIL3 antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-PPIL3 antibody

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Huo, D.H., et al. Biochem. Biophys. Res. Commun. 372(1):14-18(2008). Qi, Z.Y., et al. Chin. Med. J. 118(10):799-805(2005). Hillier, L.W., et al. Nature 434(7034):724-731(2005). Huang, L.L., et al. Acta Crystallogr. D Biol. Crystallogr. 61 (PT 3), 316-321 (2005).

Other Notes

Small volumes of anti-PPIL3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPIL3 purchase

MBS6336318 is an antibody targeting PPIL3. Also known as PPIL3, CT (PPIL3, Peptidyl-prolyl cis-trans isomerase-like 3, Cyclophilin J, Cyclophilin-like protein PPIL3, Rotamase PPIL3) (MaxLight 405). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PPIL3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
peptidyl-prolyl cis-trans isomerase-like 3 isoform PPIL3a
NCBI Official Synonym Full Names
peptidylprolyl isomerase (cyclophilin)-like 3
NCBI Official Symbol
PPIL3
NCBI Official Synonym Symbols
CYPJ
UniProt Protein Name
Peptidyl-prolyl cis-trans isomerase-like 3
UniProt Synonym Protein Names
Cyclophilin J; CyPJ; Cyclophilin-like protein PPIL3; Rotamase PPIL3
UniProt Gene Name
PPIL3
UniProt Synonym Gene Names
PPIase; CyPJ
UniProt Entry Name
PPIL3_HUMAN
NCBI Protein Information
peptidyl-prolyl cis-trans isomerase-like 3; PPIase; PPIase-like protein 3; cyclophilin J; cyclophilin-like protein 3; cyclophilin-like protein PPIL3; peptidylprolyl cis-trans isomerase-like protein 3; rotamase PPIL3

UniProt Comments for PPIL3

PPIL3: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing. Belongs to the cyclophilin-type PPIase family. PPIL3 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cyclophilin; EC 5.2.1.8; Isomerase; Spliceosome

Chromosomal Location of Human Ortholog: 2q33.1

Molecular Function: protein binding; peptidyl-prolyl cis-trans isomerase activity

Biological Process: nuclear mRNA splicing, via spliceosome; protein peptidyl-prolyl isomerization; protein folding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-PPIL3 antibody

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >1 publications with PPIL3 and Carcinoma
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