Rabbit Anti-PPM1G Polyclonal Antibody – Cat# MBS6336405

PPM1G Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the PPM1G antibody detected the PPM1G protein (arrow).

PPM1G Antibody – Rabbit Polyclonal

Name: PPM1G Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6336405
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6336405

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PPM1G, Polyclonal Antibody

Full Product Name

PPM1G, NT (PPM1G, PPM1C, Protein phosphatase 1G, Protein phosphatase 1C, Protein phosphatase 2C isoform gamma, Protein phosphatase magnesium-dependent 1 gamma) (Azide free) (HRP)

Product Gene Name

anti-PPM1G antibody

Product Synonym Names

PPM1G; PPM1C; Protein phosphatase 1G; Protein phosphatase 1C; Protein phosphatase 2C isoform gamma; Protein phosphatase magnesium-dependent 1 gamma

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

59,272 Da

OMIM

605119

3D Structure

ModBase 3D Structure for O15355

Immunogen

PPM1G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-92 amino acids from the N-terminal region of human PPM1G.

Conjugate

HRP

Note

Preservative Free

Product Categories/Family for anti-PPM1G antibody

Antibodies; Enzymes; Phosphatase

Applications Tested/Suitable for anti-PPM1G antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-PPM1G antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-PPM1G antibody

Dick, D.M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (6), 1179-1188 (2010): Suh, E.J., et al. Biochem. Biophys. Res. Commun. 386(3):467-470(2009). Petri, S., et al. J. Cell Biol. 179(3):451-465(2007). Allemand, E., et al. Nat. Struct. Mol. Biol. 14(7):630-638(2007). Matsuoka, S., et al. Science 316(5828):1160-1166(2007).

Other Notes

Small volumes of anti-PPM1G antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPM1G purchase

MBS6336405 is an antibody targeting PPM1G. Also known as PPM1G, NT (PPM1G, PPM1C, Protein phosphatase 1G, Protein phosphatase 1C, Protein phosphatase 2C isoform gamma, Protein phosphatase magnesium-dependent 1 gamma) (Azide free) (HRP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PPM1G. It may not necessarily be applicable to this product.

NCBI GI #

29826282

NCBI GeneID

5496

NCBI Accession #

NP_817092.1

UniProt Primary Accession #

O15355

UniProt Related Accession #

O15355

GenBank Nucleotide #

NM_177983.2

NCBI Official Full Name

protein phosphatase 1G

NCBI Official Synonym Full Names

protein phosphatase, Mg2+/Mn2+ dependent, 1G

NCBI Official Symbol

PPM1G

NCBI Official Synonym Symbols

PP2CG; PPP2CG; PP2CGAMMA

UniProt Protein Name

Protein phosphatase 1G

UniProt Synonym Protein Names

Protein phosphatase 1C; Protein phosphatase 2C isoform gamma; PP2C-gamma; Protein phosphatase magnesium-dependent 1 gamma

Protein Family

Protein phosphatase

UniProt Gene Name

PPM1G

UniProt Synonym Gene Names

PPM1C; PP2C-gamma

UniProt Entry Name

PPM1G_HUMAN

NCBI Protein Information

protein phosphatase 1G; PP2C, gamma; PP2C-gamma; protein phosphatase 1C; protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform; protein phosphatase 2, catalytic subunit, gamma isoform; protein phosphatase 2C gamma isoform; protein phosp

UniProt Comments for PPM1G

PPM1G: is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. [provided by RefSeq, Apr 2010]

Protein type: Spliceosome; Protein phosphatase, Ser/Thr (non-receptor); EC 3.1.3.16; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2p23.3

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: protein binding; metal ion binding; protein serine/threonine phosphatase activity

Biological Process: protein amino acid dephosphorylation; cell cycle arrest

Research Articles on PPM1G

1. PPM1G inactivates monomeric WWP2 and promotes the assembly of WWP2-WWP1 heterodimeric complex.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PPM1G antibody

Reference Product	PubMed Publications
USP7 antibody	>1 publications with PPM1G and USP7

Pathways associated with anti-PPM1G antibody

Products by Pathway	Pathway Diagram
MRNA Processing Pathway antibodies	MRNA Processing Pathway Diagram

Diseases associated with anti-PPM1G antibody

Disease Name	Pubmed Publications
Necrosis Antibodies	>1 publications with PPM1G and Necrosis

Organs/Tissues associated with anti-PPM1G antibody

Organ/Tissue Name	Pubmed Publications
Nerve Antibodies	>1 publications with PPM1G and Nerve
Embryonic Tissue Antibodies	>1 publications with PPM1G and Embryonic Tissue