Rabbit Anti-PPP2R5D Polyclonal Antibody – Cat# MBS6336677

PPP2R5D Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the PPP2R5D antibody detected the PPP2R5D protein (arrow).

PPP2R5D Antibody – Rabbit Polyclonal

Name: PPP2R5D Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6336677
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6336677

The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PPP2R5D, Polyclonal Antibody

Full Product Name

PPP2R5D, NT (PPP2R5D, Serine/threonine-protein phosphatase 2A 56kD regulatory subunit delta isoform, PP2A B subunit isoform B'-delta, PP2A B subunit isoform B56-delta, PP2A B subunit isoform PR61-delta, PP2A B subunit isoform R5-delta) (APC)

Product Gene Name

anti-PPP2R5D antibody

Product Synonym Names

PPP2R5D; Serine/threonine-protein phosphatase 2A 56kD regulatory subunit delta isoform; PP2A B subunit isoform B'-delta; PP2A B subunit isoform B56-delta; PP2A B subunit isoform PR61-delta; PP2A B subunit isoform R5-delta

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

OMIM

601646

3D Structure

ModBase 3D Structure for Q14738

Immunogen

PPP2R5D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-91 amino acids from the N-terminal region of human PPP2R5D.

Conjugate

APC

Note

Preservative Free

Special Handling

Light sensitive

Product Categories/Family for anti-PPP2R5D antibody

Antibodies; Enzymes; Phosphatase

Applications Tested/Suitable for anti-PPP2R5D antibody

Western Blot (WB), FLISA

Application Notes for anti-PPP2R5D antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-PPP2R5D antibody

Yu, U.Y., et al. BMB Rep 43(4):263-267(2010). Reece, K.M., et al. Biochem. Biophys. Res. Commun. 386(4):582-587(2009). Forester, C.M., et al. Proc. Natl. Acad. Sci. U.S.A. 104(50):19867-19872(2007). Sablina, A.A., et al. Cell 129(5):969-982(2007). Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007).

Other Notes

Small volumes of anti-PPP2R5D antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPP2R5D purchase

MBS6336677 is an antibody targeting PPP2R5D. Also known as PPP2R5D, NT (PPP2R5D, Serine/threonine-protein phosphatase 2A 56kD regulatory subunit delta isoform, PP2A B subunit isoform B'-delta, PP2A B subunit isoform B56-delta, PP2A B subunit isoform PR61-delta, PP2A B subunit isoform R5-delta) (APC). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PPP2R5D. It may not necessarily be applicable to this product.

NCBI GI #

31083288

NCBI GeneID

5528

NCBI Accession #

NP_851308.1

UniProt Primary Accession #

Q14738

UniProt Related Accession #

Q14738

GenBank Nucleotide #

NP_851308.1

NCBI Official Full Name

serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform 3

NCBI Official Synonym Full Names

protein phosphatase 2 regulatory subunit B'delta

NCBI Official Symbol

PPP2R5D

NCBI Official Synonym Symbols

B56D; MRD35; B56delta

UniProt Protein Name

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

UniProt Synonym Protein Names

PP2A B subunit isoform B'-delta; PP2A B subunit isoform B56-delta; PP2A B subunit isoform PR61-delta; PP2A B subunit isoform R5-delta

Protein Family

Serine/threonine-protein phosphatase

UniProt Gene Name

PPP2R5D

UniProt Entry Name

2A5D_HUMAN

NCBI Protein Information

serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

UniProt Comments for PPP2R5D

PPP2R5D: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules. Interacts with SGOL1. By retinoic acid; in neuroblastoma cell lines. Isoform Delta-2 is widely expressed. Isoform Delta-1 is highly expressed in brain. Belongs to the phosphatase 2A regulatory subunit B56 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Protein phosphatase, regulatory subunit

Chromosomal Location of Human Ortholog: 6p21.1

Cellular Component: nucleoplasm; protein phosphatase type 2A complex; cytosol; nucleus

Molecular Function: protein binding; protein phosphatase type 2A regulator activity; protein serine/threonine phosphatase activity

Biological Process: nervous system development; glycolysis; nerve growth factor receptor signaling pathway; MyD88-independent toll-like receptor signaling pathway; stress-activated MAPK cascade; glucose metabolic process; pathogenesis; toll-like receptor 3 signaling pathway; toll-like receptor 10 signaling pathway; toll-like receptor 2 signaling pathway; toll-like receptor 5 signaling pathway; MyD88-dependent toll-like receptor signaling pathway; dephosphorylation; regulation of catalytic activity; carbohydrate metabolic process; energy reserve metabolic process; toll-like receptor signaling pathway; innate immune response; toll-like receptor 9 signaling pathway; toll-like receptor 4 signaling pathway

Disease: Mental Retardation, Autosomal Dominant 35

Research Articles on PPP2R5D

1. Mutations in PPP2R5D are genetic cause of intellectual disability.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.