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PQLC2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6336843

The specific function of this protein remains unknown. There are 3 named isoforms. More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PQLC2, Polyclonal Antibody
Full Product Name
PQLC2, CT (PQLC2, PQ-loop repeat-containing protein 2) (Biotin)
Product Gene Name
anti-PQLC2 antibody
Product Synonym Names
PQLC2; PQ-loop repeat-containing protein 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
OMIM
AK000327 mRNA
3D Structure
ModBase 3D Structure for Q6ZP29
Immunogen
PQLC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-251 amino acids from the C-terminal region of human PQLC2.
Conjugate
Biotin
Note
Preservative Free

Product Categories/Family for anti-PQLC2 antibody

Antibodies; Proteins
Applications Tested/Suitable for anti-PQLC2 antibody
Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
Application Notes for anti-PQLC2 antibody
IHC: 1:10-50
ELISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-PQLC2 antibody

PQLC2 Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the PQLC2 antibody detected the PQLC2 protein (arrow).
Rabbit Anti-PQLC2 Polyclonal Antibody – Cat# MBS6336843

Immunohistochemistry (IHC) of anti-PQLC2 antibody

PQLC2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PQLC2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-PQLC2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6336843

Product References and Citations for anti-PQLC2 antibody

Gregory, S.G., et al. Nature 441(7091):315-321(2006).

Other Notes

Small volumes of anti-PQLC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PQLC2 purchase

MBS6336843 is an antibody targeting PQLC2. Also known as PQLC2, CT (PQLC2, PQ-loop repeat-containing protein 2) (Biotin). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PQLC2. It may not necessarily be applicable to this product.

NCBI GI #
92110025
NCBI GeneID
54896
NCBI Accession #
NP_060235.2
NCBI Related Accession #
NP_001035214.1
UniProt Primary Accession #
Q6ZP29
UniProt Related Accession #
Q6ZP29
GenBank Nucleotide #
NP_060235.2
NCBI Official Full Name
lysosomal amino acid transporter 1 homolog isoform 1
NCBI Official Synonym Full Names
solute carrier family 66 member 1
NCBI Official Symbol
SLC66A1
NCBI Official Synonym Symbols
LAAT1; PQLC2; LAAT-1
UniProt Protein Name
Lysosomal amino acid transporter 1 homolog
UniProt Synonym Protein Names
PQ-loop repeat-containing protein 2
Protein Family
Lysosomal amino acid transporter
UniProt Gene Name
PQLC2
NCBI Protein Information
lysosomal amino acid transporter 1 homolog

UniProt Comments for PQLC2

PQLC2: Lysosomal lysine/arginine transporter that specifically mediates the export of lysine and arginine from lysosomes. Belongs to the laat-1 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p36.13

Cellular Component: intracellular membrane-bound organelle; lysosomal membrane

Molecular Function: arginine transmembrane transporter activity; basic amino acid transmembrane transporter activity; L-lysine transmembrane transporter activity

Biological Process: arginine transport; lysine transport; transmembrane transport
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Research Articles on PQLC2

1. knockdown caused growth arrest and cell death of cancer cells and suppressed tumor growth in a mouse xenograft model. These results suggest that targeting PQLC2 is an effective strategy for GC treatment.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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