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PURG Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6339177

The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PUR,… More details

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Product Overview

Online Datasheet in PDF
Product Name
PURG, Polyclonal Antibody
Full Product Name
PURG, CT (PURG, Purine-rich element-binding protein gamma) (Azide free) (HRP)
Product Gene Name
anti-PURG antibody
Product Synonym Names
PURG; Purine-rich element-binding protein gamma
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
39,556 Da
Chromosome Location
Chromosome: 8; NC_000008.10 (30853320..30891231, complement). Location: 8p11
3D Structure
ModBase 3D Structure for Q9UJV8
Immunogen
PURG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-261 amino acids from the C-terminal region of human PURG.
Conjugate
HRP
Note
Preservative Free

Product Categories/Family for anti-PURG antibody

Antibodies; Binding Proteins
Applications Tested/Suitable for anti-PURG antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-PURG antibody
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-PURG antibody

PURG Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PURG antibody detected the PURG protein (arrow).
Rabbit Anti-PURG Polyclonal Antibody – Cat# MBS6339177

Flow Cytometry (FC/FACS) of anti-PURG antibody

PURG Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-PURG Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS6339177

Product References and Citations for anti-PURG antibody

Liu, H., et al. Nucleic Acids Res. 30(11):2417-2426(2002).

Other Notes

Small volumes of anti-PURG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PURG purchase

MBS6339177 is an antibody targeting PURG. Also known as PURG, CT (PURG, Purine-rich element-binding protein gamma) (Azide free) (HRP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PURG. It may not necessarily be applicable to this product.

NCBI GI #
62865862
NCBI GeneID
29942
NCBI Accession #
NP_001015508.1
NCBI Related Accession #
NP_037489.1
UniProt Primary Accession #
Q9UJV8
UniProt Secondary Accession #
Q8TE64
UniProt Related Accession #
Q9UJV8
GenBank Nucleotide #
NM_001015508.1
NCBI Official Full Name
purine-rich element-binding protein gamma isoform B
NCBI Official Synonym Full Names
purine-rich element binding protein G
NCBI Official Symbol
PURG
NCBI Official Synonym Symbols
PURG-A; PURG-B
UniProt Protein Name
Purine-rich element-binding protein gamma
Protein Family
Purine-rich element-binding protein
UniProt Gene Name
PURG
UniProt Entry Name
PURG_HUMAN
NCBI Protein Information
purine-rich element-binding protein gamma; Pur-gamma

NCBI Summary for PURG

The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PUR, and has been implicated in the control of both DNA replication and transcription. This gene lies in close proximity to the Werner syndrome gene, but on the opposite strand, on chromosome 8p11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for PURG

PURG: The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PUR, and has been implicated in the control of both DNA replication and transcription. This gene lies in close proximity to the Werner syndrome gene, but on the opposite strand, on chromosome 8p11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 8p11

Cellular Component: nucleus

Molecular Function: DNA binding
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Research Articles on PURG

1. Distinct proteins encoded by alternative transcripts of the PURG gene, located contrapodal to WRN on chromosome 8, determined by differential termination/polyadenylation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PURG antibody

 Reference Product  PubMed Publications
 WRN antibody  >1 publications with PURG and WRN
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