Rabbit Anti-QTRTD1 Polyclonal Antibody – Cat# MBS6339486

QTRTD1 Antibody – Rabbit Polyclonal

Name: QTRTD1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6339486
Price: 1025 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6339486

Interacts with QTRT1 to form an active queuine tRNA-ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp,-Asn,-His and-Tyr), thereby forming the hypermodified nucleoside queuosine… More details

$1025 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

QTRTD1, Polyclonal Antibody

Full Product Name

QTRTD1, CT (QTRTD1, Queuine tRNA-ribosyltransferase subunit QTRTD1, Queuine tRNA-ribosyltransferase domain-containing protein 1) (MaxLight 405)

Product Gene Name

anti-QTRTD1 antibody

Product Synonym Names

QTRTD1; Queuine tRNA-ribosyltransferase subunit QTRTD1; Queuine tRNA-ribosyltransferase domain-containing protein 1

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

3D Structure

ModBase 3D Structure for Q9H974

Immunogen

QTRTD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 328-359 amino acids from the C-terminal region of human QTRTD1.

Conjugate

MaxLight405

Note

Preservative Free

Product Categories/Family for anti-QTRTD1 antibody

Antibodies; Enzymes; Ribosyltransferase

Applications Tested/Suitable for anti-QTRTD1 antibody

Flow Cytometry (FC/FACS), FLISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)

Application Notes for anti-QTRTD1 antibody

FC/FACS: 1:10-50
FLISA: 1:1,000
IF: 1:10-50
IHC: 1:10-50
WB: 1:100-500
Applications are based on unconjugated antibody.

Product References and Citations for anti-QTRTD1 antibody

Chen, Y.C., et al. RNA 16(5):958-968(2010). Lamesch, P., et al. Genomics 89(3):307-315(2007).

Other Notes

Small volumes of anti-QTRTD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for QTRTD1 purchase

MBS6339486 is an antibody targeting QTRTD1. Also known as QTRTD1, CT (QTRTD1, Queuine tRNA-ribosyltransferase subunit QTRTD1, Queuine tRNA-ribosyltransferase domain-containing protein 1) (MaxLight 405). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for QTRTD1. It may not necessarily be applicable to this product.

NCBI GI #

13375872

NCBI GeneID

79691

NCBI Accession #

NP_078914.1

UniProt Primary Accession #

Q9H974

UniProt Related Accession #

Q9H974

GenBank Nucleotide #

NP_078914.1

NCBI Official Full Name

queuine tRNA-ribosyltransferase accessory subunit 2 isoform 1

NCBI Official Synonym Full Names

queuine tRNA-ribosyltransferase accessory subunit 2

NCBI Official Symbol

QTRT2

NCBI Official Synonym Symbols

QTRTD1

UniProt Protein Name

Queuine tRNA-ribosyltransferase subunit QTRTD1

UniProt Synonym Protein Names

Queuine tRNA-ribosyltransferase domain-containing protein 1

UniProt Gene Name

QTRTD1

UniProt Entry Name

QTRD1_HUMAN

NCBI Protein Information

queuine tRNA-ribosyltransferase accessory subunit 2

NCBI Summary for QTRTD1

This gene encodes a subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine, and tyrosine. The encoded protein may play a role in the queuosine 5'-monophosphate salvage pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]

UniProt Comments for QTRTD1

QTRTD1: Interacts with QTRT1 to form an active queuine tRNA- ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1- yl)amino)methyl)-7-deazaguanosine). Belongs to the queuine tRNA-ribosyltransferase family. QTRTD1 subfamily.

Protein type: EC 2.4.2.29

Chromosomal Location of Human Ortholog: 3q13.31

Cellular Component: cytoplasm; mitochondrial outer membrane; mitochondrion

Molecular Function: protein heterodimerization activity; protein homodimerization activity; queuine tRNA-ribosyltransferase activity

Biological Process: queuosine biosynthetic process; tRNA modification

Research Articles on QTRTD1

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-QTRTD1 antibody

Reference Product	PubMed Publications
QTRT1 antibody	>2 publications with QTRTD1 and QTRT1