Rabbit Anti-RAB28 Polyclonal Antibody – Cat# MBS6339696

RAB28 Antibody – Rabbit Polyclonal

Name: RAB28 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6339696
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6339696

This gene encodes a member of the Rab subfamily of Ras-related small GTPases. The encoded protein may be involved in regulating intracellular trafficking. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on… More details

$1060 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RAB28, Polyclonal Antibody

Full Product Name

RAB28, ID (RAB28, Ras-related protein Rab-28) (MaxLight 490)

Product Gene Name

anti-RAB28 antibody

Product Synonym Names

RAB28; Ras-related protein Rab-28

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

OMIM

612994

3D Structure

ModBase 3D Structure for P51157

Immunogen

RAB28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-147 amino acids from the Central region of human RAB28.

Conjugate

MaxLight490

Note

Preservative Free

Product Categories/Family for anti-RAB28 antibody

Antibodies; GTPase; Rab; Ras; Rho Proteins

Applications Tested/Suitable for anti-RAB28 antibody

Western Blot (WB), FLISA

Application Notes for anti-RAB28 antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-RAB28 antibody

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Lee, S.H., et al. FEBS Lett. 582(29):4107-4111(2008). Lamesch, P., et al. Genomics 89(3):307-315(2007). Stenmark, H., et al. Genome Biol. 2 (5), REVIEWS3007 (2001): Pereira-Leal, J.B., et al. J. Mol. Biol. 301(4):1077-1087(2000).

Other Notes

Small volumes of anti-RAB28 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAB28 purchase

MBS6339696 is an antibody targeting RAB28. Also known as RAB28, ID (RAB28, Ras-related protein Rab-28) (MaxLight 490). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB28. It may not necessarily be applicable to this product.

NCBI GI #

227497996

NCBI GeneID

9364

NCBI Accession #

NP_004240.2

NCBI Related Accession #

NP_001017979.1

UniProt Primary Accession #

P51157

UniProt Related Accession #

P51157

GenBank Nucleotide #

NP_004240.2

NCBI Official Full Name

ras-related protein Rab-28 isoform 2

NCBI Official Synonym Full Names

RAB28, member RAS oncogene family

NCBI Official Symbol

RAB28

NCBI Official Synonym Symbols

CORD18

UniProt Protein Name

Ras-related protein Rab-28

Protein Family

Late embryogenesis abundant protein

UniProt Gene Name

RAB28

UniProt Entry Name

RAB28_HUMAN

NCBI Protein Information

ras-related protein Rab-28

UniProt Comments for RAB28

Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side

Potential. Cytoplasm › cytoskeleton › cilium basal body. Note: Expressed in the basal body and ciliary rootlet of the photoreceptors

By similarity.

Tissue specificity: Isoform S is detected in most tissues investigated: cortex, liver, kidney, skeletal muscle, adipose tissue, testis, urothelium, lung, bone marrow and retinal pigment epithelium (RPE). Isoform L 2 is widely and abundantly expressed all tissues. Isoform 3 is highly expressed in heart, lung, bone marrow, retina, brain, and RPE.

Involvement in disease: Cone-rod dystrophy 18 (CORD18) [MIM:615374]: A form of cone-rod dystrophy, an inherited retinal dystrophy characterized by retinal pigment deposits visible on fundus examination, predominantly in the macular region, and initial loss of cone photoreceptors followed by rod degeneration. This leads to decreased visual acuity and sensitivity in the central visual field, followed by loss of peripheral vision. Severe loss of vision occurs earlier than in retinitis pigmentosa.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.8

Sequence similarities: Belongs to the small GTPase superfamily. Rab family.

Research Articles on RAB28

1. In conclusion, RAB28 variants are a rare cause of cone-rod dystrophy in various ethnic groups. These variants cause a comparable ophthalmological phenotype and furthermore could also be a cause of postaxial polydactyly.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.