• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

RPA43 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6343201

RPA43 is DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. It is component of RNA polymerase I which synthesizes ribosomal RNA precursors. Through its association with… More details

$1060 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RPA43, Polyclonal Antibody
Full Product Name
RPA43, CT (TWISTNB, DNA-directed RNA polymerase I subunit RPA43, Twist neighbor protein) (MaxLight 650)
Product Gene Name
anti-RPA43 antibody
Product Synonym Gene Name
TWISTNB
Product Synonym Names
TWISTNB; DNA-directed RNA polymerase I subunit RPA43; Twist neighbor protein
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
37,432 Da
OMIM
AK301329 mRNA
3D Structure
ModBase 3D Structure for Q3B726
Immunogen
RPA43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-336 amino acids from the C-terminal region of human RPA43.
Conjugate
MaxLight650
Note
Preservative Free

Product Categories/Family for anti-RPA43 antibody

Antibodies; DNA Replication; Repair
Applications Tested/Suitable for anti-RPA43 antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes for anti-RPA43 antibody
IHC: 1:50-100
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.

Product References and Citations for anti-RPA43 antibody

Olsen, J.V., et al. Cell 127(3):635-648(2006). Yuan, X., et al. EMBO Rep. 3(11):1082-1087(2002). Kosan, C., et al. Cytogenet. Genome Res. 97 (3-4), 167-170 (2002).

Other Notes

Small volumes of anti-RPA43 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RPA43 purchase

MBS6343201 is an antibody targeting RPA43. Also known as RPA43, CT (TWISTNB, DNA-directed RNA polymerase I subunit RPA43, Twist neighbor protein) (MaxLight 650). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RPA43. It may not necessarily be applicable to this product.

NCBI GI #
121942339
NCBI GeneID
221830
NCBI Accession #
Q3B726.1
UniProt Primary Accession #
Q3B726
UniProt Secondary Accession #
A0PJ45; B7Z724
UniProt Related Accession #
Q3B726
NCBI Official Full Name
DNA-directed RNA polymerase I subunit RPA43
NCBI Official Synonym Full Names
TWIST neighbor
NCBI Official Symbol
TWISTNB
UniProt Protein Name
DNA-directed RNA polymerase I subunit RPA43
UniProt Synonym Protein Names
Twist neighbor protein
Protein Family
DNA-directed RNA polymerase
UniProt Gene Name
TWISTNB
NCBI Protein Information
DNA-directed RNA polymerase I subunit RPA43

UniProt Comments for RPA43

TWISTNB: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters. Belongs to the eukaryotic RPA43 RNA polymerase subunit family.

Protein type: Nucleolus

Chromosomal Location of Human Ortholog: 7p21.1

Cellular Component: DNA-directed RNA polymerase I complex; microtubule cytoskeleton; nucleolus; nucleoplasm; nucleus

Biological Process: positive regulation of gene expression, epigenetic; RNA elongation from RNA polymerase I promoter; termination of RNA polymerase I transcription; transcription initiation from RNA polymerase I promoter
Show more

Research Articles on RPA43

1. describe the localisation and characterisation of the TWIST NEIGHBOR (TWISTNB) gene

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-RPA43 antibody

 Products by Pathway  Pathway Diagram
 B-WICH Complex Positively Regulates RRNA Expression Pathway antibodies  B-WICH Complex Positively Regulates RRNA Expression Pathway Diagram
 Epigenetic Regulation Of Gene Expression Pathway antibodies  Epigenetic Regulation Of Gene Expression Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Negative Epigenetic Regulation Of RRNA Expression Pathway antibodies  Negative Epigenetic Regulation Of RRNA Expression Pathway Diagram
 NoRC Negatively Regulates RRNA Expression Pathway antibodies  NoRC Negatively Regulates RRNA Expression Pathway Diagram
 Positive Epigenetic Regulation Of RRNA Expression Pathway antibodies  Positive Epigenetic Regulation Of RRNA Expression Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram

Diseases associated with anti-RPA43 antibody

 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >1 publications with RPA43 and Congenital Abnormalities

Organs/Tissues associated with anti-RPA43 antibody

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >1 publications with RPA43 and Skin
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000