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Plasminogen Activator Inhibitor Type 1 P14 Arg, Stable Mutant Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS634604

PAI-1 protein has a single substitution at either the P12 or P14 position on the reactive center loop facilitating a conversion of the proteins to a substrate for proteases rather than an inhibitor. Useful for mechanistic studies. More details

$1730 / 0.5 mg +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Plasminogen Activator Inhibitor Type 1 P14 Arg, stable mutant, Active Protein
Full Product Name
Plasminogen Activator Inhibitor Type 1 P14 Arg, stable mutant, Human (PAI-1)
Host
PAI-1 from human plasma
Form/Format
Supplied as a liquid in 0.5M sodium phosphate, 0.15M sodium chloride, pH 6.6.
Purity/Purification
Highly Purified
~98% (SDS-PAGE)
Preparation and Storage
Aliquot to avoid repeated freezing and thawing and store at -70 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
~43kD
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Activity
Substitution at the P14 position on the reactive center loop creates a PAI-1 substrate for proteinases rather than an inhibitor.
Absorption
280nm
Solubility
2~5mg/ml

Other Notes

Small volumes of Plasminogen Activator Inhibitor Type 1 P14 Arg, stable mutant active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Plasminogen Activator Inhibitor Type 1 P14 Arg, stable mutant purchase

MBS634604 is an active protein targeting Plasminogen Activator Inhibitor Type 1 P14 Arg, stable mutant. Also known as Plasminogen Activator Inhibitor Type 1 P14 Arg, stable mutant, Human (PAI-1). Host: PAI-1 from human plasma.
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