Rabbit Anti-SGTA Polyclonal Antibody – Cat# MBS6347101

SGTA Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the SGTA antibody detected the SGTA protein (arrow).

SGTA Antibody – Rabbit Polyclonal

Name: SGTA Antibody; Polyclonal; Rabbit; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6347101
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6347101

This gene encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein; however, its function is not known. Since this transcript is expressed ubiquitously in various tissues,… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SGTA, Polyclonal Antibody

Full Product Name

SGTA, ID (SGTA, SGT, SGT1, Small glutamine-rich tetratricopeptide repeat-containing protein alpha, Alpha-SGT, Vpu-binding protein) (FITC)

Product Gene Name

anti-SGTA antibody

Product Synonym Names

SGTA; SGT; SGT1; Small glutamine-rich tetratricopeptide repeat-containing protein alpha; Alpha-SGT; Vpu-binding protein

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Mouse

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

34,063 Da

OMIM

603419

3D Structure

ModBase 3D Structure for O43765

Immunogen

SGTA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-106 amino acids from the Central region of human SGTA.

Conjugate

FITC

Note

Preservative Free

Special Handling

Light sensitive

Product Categories/Family for anti-SGTA antibody

Antibodies; Tetratricopeptide Repeat Proteins

Applications Tested/Suitable for anti-SGTA antibody

Western Blot (WB), FLISA

Application Notes for anti-SGTA antibody

WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-SGTA antibody

Ewens, K.G., et al. J. Clin. Endocrinol. Metab. 95(5):2306-2315(2010). Dutta, S., et al. Biochemistry 47(38):10123-10131(2008). Dutta, S., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 64 (PT 7), 602-604 (2008): Goodarzi, M.O., et al. Hum. Reprod. 23(5):1214-1219(2008). Buchanan, G., et al. Cancer Res. 67(20):10087-10096(2007).

Other Notes

Small volumes of anti-SGTA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SGTA purchase

MBS6347101 is an antibody targeting SGTA. Also known as SGTA, ID (SGTA, SGT, SGT1, Small glutamine-rich tetratricopeptide repeat-containing protein alpha, Alpha-SGT, Vpu-binding protein) (FITC). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SGTA. It may not necessarily be applicable to this product.

NCBI GI #

4506921

NCBI GeneID

6449

NCBI Accession #

NP_003012.1

UniProt Primary Accession #

O43765

UniProt Secondary Accession #

Q6FIA9; Q9BTZ9; D6W610

UniProt Related Accession #

O43765

GenBank Nucleotide #

NM_003021.3

NCBI Official Full Name

small glutamine-rich tetratricopeptide repeat-containing protein alpha

NCBI Official Synonym Full Names

small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha

NCBI Official Symbol

SGTA

NCBI Official Synonym Symbols

SGT; hSGT; alphaSGT

UniProt Protein Name

Small glutamine-rich tetratricopeptide repeat-containing protein alpha

UniProt Synonym Protein Names

Alpha-SGT; Vpu-binding protein; UBP

Protein Family

Small glutamine-rich tetratricopeptide repeat-containing protein

UniProt Gene Name

SGTA

UniProt Synonym Gene Names

SGT; SGT1; UBP

UniProt Entry Name

SGTA_HUMAN

NCBI Protein Information

small glutamine-rich tetratricopeptide repeat-containing protein alpha; UBP; alpha-SGT; protein containing three tetratricopeptide repeats; vpu-binding protein

NCBI Summary for SGTA

UniProt Comments for SGTA

SGTA: Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. Homooligomerize. Interacts with NS1 from parvovirus H-1, with Vpu and Gag from HIV-1. Interacts with SARS- CoV accessory protein 7a. Interacts with DNAJC5 and DNAJC5B. Ubiquitous. Belongs to the SGT family.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 19p13

Cellular Component: cytoplasm

Molecular Function: protein binding

Biological Process: viral reproduction

Research Articles on SGTA

1. Our data suggest a role for SGTA at distinct steps in the chaperone-dependent modulation of androgen, glucocorticoid, and progesterone receptor activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SGTA antibody

Reference Product	PubMed Publications
HSPA8 antibody	>6 publications with SGTA and HSPA8
UBL4A antibody	>4 publications with SGTA and UBL4A

Diseases associated with anti-SGTA antibody

Disease Name	Pubmed Publications
Ovarian Diseases Antibodies	>5 publications with SGTA and Ovarian Diseases
Genital Diseases, Male Antibodies	>3 publications with SGTA and Genital Diseases, Male
Prostatic Diseases Antibodies	>3 publications with SGTA and Prostatic Diseases
Liver Neoplasms Antibodies	>2 publications with SGTA and Liver Neoplasms
Liver Diseases Antibodies	>2 publications with SGTA and Liver Diseases
Neoplasms, Experimental Antibodies	>1 publications with SGTA and Neoplasms, Experimental
Hyperplasia Antibodies	>1 publications with SGTA and Hyperplasia
Disease Models, Animal Antibodies	>1 publications with SGTA and Disease Models, Animal
Inflammation Antibodies	>1 publications with SGTA and Inflammation
Kidney Diseases Antibodies	>1 publications with SGTA and Kidney Diseases

Organs/Tissues associated with anti-SGTA antibody

Organ/Tissue Name	Pubmed Publications
Prostate Antibodies	>5 publications with SGTA and Prostate
Ovary Antibodies	>4 publications with SGTA and Ovary
Brain Antibodies	>4 publications with SGTA and Brain
Liver Antibodies	>3 publications with SGTA and Liver
Nerve Antibodies	>1 publications with SGTA and Nerve
Muscle Antibodies	>1 publications with SGTA and Muscle
Kidney Antibodies	>1 publications with SGTA and Kidney
Lung Antibodies	>1 publications with SGTA and Lung
Placenta Antibodies	>1 publications with SGTA and Placenta