Annexin II, P11, Positive Control Protein

p11 is the light chain component of the Calpactin complex and a member of the S100 family of proteins that can form a heterotetramer. The functional complex is formed by the interaction of two heavy chains (annexin II) and two light chains (p11). It is important for many cellular processes, including Ca2+-dependent exocytosis, non-constitutive secretory pathways, and the correct trafficking vesicles as well as proteins out of the cell. Recently, p11 was shown to be the critical component involved in the plasma membrane translocation of NAV1.8, a subunit of the tetrodotoxin-resistant sodium channel found in sensory neurons.

Small volumes of Annexin II, p11, Positive Control protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS634829 is a protein targeting Annexin II, p11, Positive Control. Also known as Annexin II, p11, Positive Control (KLH).