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Insulin, Porcine (INS) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS634891

Insulin Porcine is a two chain, glycosylated polypeptide chain containing 51 amino acids and having a molecular mass of 5.77kD. The a and b chains are joined by two interchain disulfide bonds. The a chain contains an intrachain disulfide bond. Insulin… More details

$565 / 0.025 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Insulin, Porcine, Active Protein
Full Product Name
Insulin, Porcine
Product Gene Name
INS active protein
Host
Porcine Pancreas
Form/Format
Supplied lyophilized from a concentrated 1mg/ml solution with no additives. Reconstitute with sterile dH2O to 100ug/ml, which can then be further diluted to other aqueous solutions.
Purity/Purification
Highly Purified
98.0% as determined by RP-HPLC or SDS-PAGE.
Preparation and Storage
Although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein, 0.1% HSA or BSA. Please prevent freeze-thaw cycles.
Molecular Weight
5.77kD
Chromosome Location
2; 2
3D Structure
ModBase 3D Structure for P01315
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Biological Activity
~25 units/mg

Product Categories/Family for INS active protein

Molecular Biology; MB-Insulin

Other Notes

Small volumes of INS active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for INS purchase

MBS634891 is an active protein targeting INS. Also known as Insulin, Porcine. Host: Porcine Pancreas.

Additional Details

NCBI/Uniprot data below describe general gene information for INS. It may not necessarily be applicable to this product.

NCBI GI #
12643972
NCBI GeneID
397415
NCBI Accession #
P01315.2
UniProt Primary Accession #
P01315
UniProt Secondary Accession #
Q9TSJ5
UniProt Related Accession #
P01315
NCBI Official Full Name
Insulin
NCBI Official Symbol
INS
UniProt Protein Name
Insulin
Protein Family
Insulin
UniProt Gene Name
INS
UniProt Entry Name
INS_PIG
NCBI Protein Information
insulin; proinsulin; preproinsulin

UniProt Comments for INS

Function: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.

Subunit structure: Heterodimer of a B chain and an A chain linked by two disulfide bonds.

Subcellular location: Secreted.

Sequence similarities: Belongs to the insulin family.

Sequence caution: The sequence AAC77920.1 differs from that shown. Reason: Erroneous initiation.
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Research Articles on INS

1. Data suggest that a mutation in INS (C94Y) results a transgenic disease model for the investigation of permanent neonatal diabetes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with INS active protein

 Products by Pathway  Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 Aldosterone-regulated Sodium Reabsorption Pathway antibodies  Aldosterone-regulated Sodium Reabsorption Pathway Diagram
 HIF-1 Signaling Pathway antibodies  HIF-1 Signaling Pathway Diagram
 Insulin Secretion Pathway antibodies  Insulin Secretion Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram
 Maturity Onset Diabetes Of The Young Pathway antibodies  Maturity Onset Diabetes Of The Young Pathway Diagram
 Maturity Onset Diabetes Of The Young Pathway antibodies  Maturity Onset Diabetes Of The Young Pathway Diagram
 Non-alcoholic Fatty Liver Disease (NAFLD) Pathway antibodies  Non-alcoholic Fatty Liver Disease (NAFLD) Pathway Diagram
 Non-alcoholic Fatty Liver Disease (NAFLD) Pathway antibodies  Non-alcoholic Fatty Liver Disease (NAFLD) Pathway Diagram

Diseases associated with INS active protein

 Disease Name  Pubmed Publications
 Metabolic Diseases Antibodies  >1003 publications with INS and Metabolic Diseases
 Diabetes Mellitus Antibodies  >819 publications with INS and Diabetes Mellitus
 Insulin Resistance Antibodies  >300 publications with INS and Insulin Resistance
 Diabetes Mellitus, Type 2 Antibodies  >276 publications with INS and Diabetes Mellitus, Type 2
 Obesity Antibodies  >221 publications with INS and Obesity
 Hyperinsulinism Antibodies  >200 publications with INS and Hyperinsulinism
 Hyperglycemia Antibodies  >198 publications with INS and Hyperglycemia
 Hypertension Antibodies  >120 publications with INS and Hypertension
 Polycystic Ovary Syndrome Antibodies  >52 publications with INS and Polycystic Ovary Syndrome
 Hypoglycemia Antibodies  >46 publications with INS and Hypoglycemia
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