Rabbit Anti-SSRP1 Polyclonal Antibody – Cat# MBS6351369

SSRP1 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the SSRP1 antibody detected the SSRP1 protein (arrow).

SSRP1 Antibody – Rabbit Polyclonal

Name: SSRP1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6351369
Price: 1060 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6351369

The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation.… More details

$1060 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SSRP1, Polyclonal Antibody

Full Product Name

SSRP1, CT (SSRP1, FACT80, FACT complex subunit SSRP1, Chromatin-specific transcription elongation factor 80kD subunit, Facilitates chromatin transcription complex 80kD subunit, Facilitates chromatin transcription complex subunit SSRP1, Recombination signa

Product Gene Name

anti-SSRP1 antibody

Product Synonym Names

SSRP1; FACT80; FACT complex subunit SSRP1; Chromatin-specific transcription elongation factor 80kD subunit; Facilitates chromatin transcription complex 80kD subunit; Facilitates chromatin transcription complex subunit SSRP1; Recombination signal sequence recognition protein 1; Structure-specific recognition protein 1; T160

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

81,075 Da

OMIM

604328

3D Structure

ModBase 3D Structure for Q08945

Immunogen

SSRP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 489-518 amino acids from the C-terminal region of human SSRP1.

Conjugate

Biotin

Note

Preservative Free

Product Categories/Family for anti-SSRP1 antibody

Antibodies; Chromatin Proteins

Applications Tested/Suitable for anti-SSRP1 antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-SSRP1 antibody

WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-SSRP1 antibody

Zeng, S.X., et al. Mol. Cell. Biol. 30(4):935-947(2010). Hautbergue, G.M., et al. Curr. Biol. 19(22):1918-1924(2009). Hu, J., et al. J. Virol. 83(21):11051-11063(2009). Kumari, A., et al. J. Cell. Biochem. 108(2):508-518(2009). Okada, M., et al. Mol. Biol. Cell 20(18):3986-3995(2009).

Other Notes

Small volumes of anti-SSRP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SSRP1 purchase

MBS6351369 is an antibody targeting SSRP1. Also known as SSRP1, CT (SSRP1, FACT80, FACT complex subunit SSRP1, Chromatin-specific transcription elongation factor 80kD subunit, Facilitates chromatin transcription complex 80kD subunit, Facilitates chromatin transcription complex subunit SSRP1, Recombination signa. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SSRP1. It may not necessarily be applicable to this product.

NCBI GI #

4507241

NCBI GeneID

6749

NCBI Accession #

NP_003137.1

UniProt Primary Accession #

Q08945

UniProt Secondary Accession #

Q5BJG8

UniProt Related Accession #

Q08945

GenBank Nucleotide #

NM_003146.2

NCBI Official Full Name

FACT complex subunit SSRP1

NCBI Official Synonym Full Names

structure specific recognition protein 1

NCBI Official Symbol

SSRP1

NCBI Official Synonym Symbols

FACT; T160; FACT80

UniProt Protein Name

FACT complex subunit SSRP1

UniProt Synonym Protein Names

Chromatin-specific transcription elongation factor 80 kDa subunit; Facilitates chromatin transcription complex 80 kDa subunit; FACT 80 kDa subunit; FACTp80; Facilitates chromatin transcription complex subunit SSRP1; Recombination signal sequence recognition protein 1; Structure-specific recognition protein 1; hSSRP1; T160

Protein Family

FACT complex

UniProt Gene Name

SSRP1

UniProt Synonym Gene Names

FACT80; FACT 80 kDa subunit; FACTp80; hSSRP1

UniProt Entry Name

SSRP1_HUMAN

NCBI Protein Information

FACT complex subunit SSRP1; hSSRP1; FACTp80; cisplatin-DNA SSRP; FACT 80 kDa subunit; high mobility group box; structure-specific recognition protein 1; facilitates chromatin remodeling 80 kDa subunit; recombination signal sequence recognition protein 1;

UniProt Comments for SSRP1

SSRP1: a subunit of the chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63.

Protein type: Transcription initiation complex; Transcription, coactivator/corepressor; RNA-binding; Nucleolus

Chromosomal Location of Human Ortholog: 11q12

Cellular Component: nucleoplasm; cytoplasm; nucleolus; chromosome; nucleus

Molecular Function: protein binding; DNA binding; chromatin binding

Biological Process: transcription from RNA polymerase II promoter; chromatin remodeling; regulation of transcription, DNA-dependent; viral reproduction; positive regulation of viral transcription; RNA elongation from RNA polymerase II promoter; gene expression; DNA repair; DNA replication

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SSRP1 antibody

Reference Product	PubMed Publications
SUPT16H antibody	>19 publications with SSRP1 and SUPT16H
SRF antibody	>2 publications with SSRP1 and SRF
CHD1 antibody	>2 publications with SSRP1 and CHD1
SUPT4H1 antibody	>1 publications with SSRP1 and SUPT4H1
MCM4 antibody	>1 publications with SSRP1 and MCM4
MCM2 antibody	>1 publications with SSRP1 and MCM2

Pathways associated with anti-SSRP1 antibody

Products by Pathway	Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Formation Of HIV Elongation Complex In The Absence Of HIV Tat Pathway antibodies	Formation Of HIV Elongation Complex In The Absence Of HIV Tat Pathway Diagram
Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway antibodies	Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway Diagram
Formation Of RNA Pol II Elongation Complex Pathway antibodies	Formation Of RNA Pol II Elongation Complex Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
HIV Infection Pathway antibodies	HIV Infection Pathway Diagram
HIV Life Cycle Pathway antibodies	HIV Life Cycle Pathway Diagram
HIV Transcription Elongation Pathway antibodies	HIV Transcription Elongation Pathway Diagram
HIV Elongation Arrest And Recovery Pathway antibodies	HIV Elongation Arrest And Recovery Pathway Diagram
Late Phase Of HIV Life Cycle Pathway antibodies	Late Phase Of HIV Life Cycle Pathway Diagram

Diseases associated with anti-SSRP1 antibody

Disease Name	Pubmed Publications
Death Antibodies	>5 publications with SSRP1 and Death
Cell Transformation, Neoplastic Antibodies	>3 publications with SSRP1 and Cell Transformation, Neoplastic
Skin Diseases Antibodies	>2 publications with SSRP1 and Skin Diseases
Immune System Diseases Antibodies	>2 publications with SSRP1 and Immune System Diseases
Disease Models, Animal Antibodies	>2 publications with SSRP1 and Disease Models, Animal
Necrosis Antibodies	>2 publications with SSRP1 and Necrosis
Nervous System Diseases Antibodies	>1 publications with SSRP1 and Nervous System Diseases
Urinary Bladder Neoplasms Antibodies	>1 publications with SSRP1 and Urinary Bladder Neoplasms
Liver Neoplasms Antibodies	>1 publications with SSRP1 and Liver Neoplasms
Neoplasms, Experimental Antibodies	>1 publications with SSRP1 and Neoplasms, Experimental

Organs/Tissues associated with anti-SSRP1 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>8 publications with SSRP1 and Blood
Muscle Antibodies	>5 publications with SSRP1 and Muscle
Lung Antibodies	>3 publications with SSRP1 and Lung
Kidney Antibodies	>2 publications with SSRP1 and Kidney
Vascular Antibodies	>1 publications with SSRP1 and Vascular
Liver Antibodies	>1 publications with SSRP1 and Liver
Bladder Antibodies	>1 publications with SSRP1 and Bladder
Brain Antibodies	>1 publications with SSRP1 and Brain
Embryonic Tissue Antibodies	>1 publications with SSRP1 and Embryonic Tissue